STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
GPCPD1Glycerophosphocholine phosphodiesterase 1. (683 aa)    
Predicted Functional Partners:
LYPLA2
PITH domain containing 1.
    
 0.925
CHAT
Choline O-acetyltransferase; Belongs to the carnitine/choline acetyltransferase family.
   
 
 0.907
ACHE
Carboxylic ester hydrolase; Belongs to the type-B carboxylesterase/lipase family.
    
 0.894
PHOSPHO1
Phosphoethanolamine/phosphocholine phosphatase.
   
 
 0.892
ETNK1
Ethanolamine kinase 1.
     
 0.891
ETNK2
Ethanolamine kinase 2.
     
 0.889
PLA2G15
Group XV phospholipase A2; Has transacylase and calcium-independent phospholipase A2 activity. Catalyzes the formation of 1-O-acyl-N-acetylsphingosine and the concomitant release of a lyso-phospholipid. Has high activity with 1-palmitoyl-2-oleoyl-sn-glycero-3-phosphocholine (POPC) and 1,2-dioleoyl-sn-glycero-3-phosphocholine (DOPC), catalyzing the transfer of oleic acid to N-acetyl-sphingosine. Required for normal phospholipid degradation in alveolar and peritoneal macrophages and in spleen (By similarity).
     
 0.889
PLB1
Phospholipase B1.
     
 0.884
MCOLN1
Patatin like phospholipase domain containing 6.
    
 0.848
PNPLA7
Patatin like phospholipase domain containing 7.
    
 0.848
Your Current Organism:
Canis lupus familiaris
NCBI taxonomy Id: 9615
Other names: C. lupus familiaris, Canis canis, Canis domesticus, Canis familiaris, beagle dog, beagle dogs, dog, dogs
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