STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
CAPN7Calpain 7; Belongs to the peptidase C2 family. (1018 aa)    
Predicted Functional Partners:
IST1
IST1 factor associated with ESCRT-III.
    
 
 0.857
LOC100856647
PKS_ER domain-containing protein.
      
 0.811
CRYZL1
PKS_ER domain-containing protein.
      
 0.811
IGF2BP2
Insulin like growth factor 2 mRNA binding protein 2.
    
   0.725
SLITRK4
SLIT and NTRK like family member 4.
    
 
 0.703
CAPNS1
Calpain small subunit 1.
   
 0.695
SPTSSB
Serine palmitoyltransferase small subunit B.
      
 0.691
CAST
Calpastatin.
   
 0.687
NXPH1
Neurexophilin; May be signaling molecules that resemble neuropeptides.
      
 0.687
GPR171
G protein-coupled receptor 171; Belongs to the G-protein coupled receptor 1 family.
      
 0.669
Your Current Organism:
Canis lupus familiaris
NCBI taxonomy Id: 9615
Other names: C. lupus familiaris, Canis canis, Canis domesticus, Canis familiaris, beagle dog, beagle dogs, dog, dogs
Server load: low (18%) [HD]