STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
FASNFatty acid synthase. (2478 aa)    
Predicted Functional Partners:
ACLY
ATP-citrate synthase; Catalyzes the cleavage of citrate into oxaloacetate and acetyl-CoA, the latter serving as common substrate for de novo cholesterol and fatty acid synthesis; In the N-terminal section; belongs to the succinate/malate CoA ligase beta subunit family.
   
 0.993
ACACA
Acetyl-CoA carboxylase alpha.
  
 
 0.991
MCAT
Malonyl-CoA-acyl carrier protein transacylase.
  
 0.978
ACACB
Acetyl-CoA carboxylase beta.
  
 
 0.972
AASDH
Aminoadipate-semialdehyde dehydrogenase.
  
 0.969
ACSL1
Acyl-CoA synthetase long chain family member 1.
   
 0.968
AASDHPPT
Aminoadipate-semialdehyde dehydrogenase-phosphopantetheinyl transferase.
  
 0.964
ACSF3
Acyl-CoA synthetase family member 3.
 
 0.956
OXSM
3-oxoacyl-[acyl-carrier-protein] synthase, mitochondrial; May play a role in the biosynthesis of lipoic acid as well as longer chain fatty acids required for optimal mitochondrial function. Belongs to the thiolase-like superfamily. Beta-ketoacyl-ACP synthases family.
  
 
0.951
ACSL3
Acyl-CoA synthetase long chain family member 3.
  
 0.948
Your Current Organism:
Canis lupus familiaris
NCBI taxonomy Id: 9615
Other names: C. lupus familiaris, Canis canis, Canis domesticus, Canis familiaris, beagle dog, beagle dogs, dog, dogs
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.