STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
LETM2Leucine zipper and EF-hand containing transmembrane protein 2. (492 aa)    
Predicted Functional Partners:
RAB11FIP1
RAB11 family interacting protein 1.
    
 
 0.868
BRF2
BRF2 RNA polymerase III transcription initiation factor subunit.
      
 0.863
GOT1L1
Glutamic-oxaloacetic transaminase 1 like 1.
   
  
 0.829
ZMAT4
Zinc finger matrin-type 4.
   
  
 0.812
EIF4EBP1
Eukaryotic translation initiation factor 4E binding protein 1.
      
 0.811
FAM118A
Family with sequence similarity 118 member A.
    
 
 0.746
TMEM39B
Transmembrane protein 39B.
      
 0.691
DNAJC18
DnaJ heat shock protein family (Hsp40) member C18.
   
 
 0.660
RHBDD3
Rhomboid domain containing 3.
      
 0.650
EXPH5
Exophilin 5.
      
 0.609
Your Current Organism:
Canis lupus familiaris
NCBI taxonomy Id: 9615
Other names: C. lupus familiaris, Canis canis, Canis domesticus, Canis familiaris, beagle dog, beagle dogs, dog, dogs
Server load: low (28%) [HD]