STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
PIK3R4Phosphoinositide-3-kinase regulatory subunit 4. (1358 aa)    
Predicted Functional Partners:
ATG14
Autophagy related 14.
    
 0.999
PIK3C3
Phosphatidylinositol 3-kinase catalytic subunit type 3.
   
 0.999
BECN1
Beclin 1.
    
 0.999
NRBF2
Nuclear receptor binding factor 2.
    
 0.998
UVRAG
UV radiation resistance associated.
    
 0.989
BECN2
Beclin 2.
    
 0.987
AMBRA1
Autophagy and beclin 1 regulator 1.
   
 
 0.984
ULK1
Unc-51 like autophagy activating kinase 1.
   
 0.964
ULK2
Unc-51 like autophagy activating kinase 2.
    
 0.955
ALKAL1
RB1 inducible coiled-coil 1.
   
 
 0.944
Your Current Organism:
Canis lupus familiaris
NCBI taxonomy Id: 9615
Other names: C. lupus familiaris, Canis canis, Canis domesticus, Canis familiaris, beagle dog, beagle dogs, dog, dogs
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.