STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
PIK3R4Phosphoinositide-3-kinase regulatory subunit 4. (1358 aa)    
Predicted Functional Partners:
ATG14
Autophagy related 14.
    
 0.999
PIK3C3
Phosphatidylinositol 3-kinase catalytic subunit type 3.
   
 0.999
BECN2
Beclin 2.
    
 0.998
BECN1
Beclin 1.
    
 0.998
UVRAG
UV radiation resistance associated.
    
 0.993
ULK1
Unc-51 like autophagy activating kinase 1.
    
 0.990
NRBF2
Nuclear receptor binding factor 2.
    
 0.990
ALKAL1
RB1 inducible coiled-coil 1.
   
 0.988
ATG13
Autophagy-related protein 13; Belongs to the ATG13 family. Metazoan subfamily.
    
 0.980
ATG101
Autophagy related 101.
     
 0.980
Your Current Organism:
Canis lupus familiaris
NCBI taxonomy Id: 9615
Other names: C. lupus familiaris, Canis canis, Canis domesticus, Canis familiaris, beagle dog, beagle dogs, dog, dogs
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.