STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
SLC16A3Solute carrier family 16 member 3. (505 aa)    
Predicted Functional Partners:
BSG
Basigin.
   
 
 0.577
SLC22A8
Solute carrier family 22 member 8.
    
 
 0.575
SLC46A3
Solute carrier family 46 member 3.
   
  
 0.573
D2HGDH
D-2-hydroxyglutarate dehydrogenase.
   
  
 0.561
SHPK
Uncharacterized protein.
    
 
 0.560
SLC2A1
Solute carrier family 2, facilitated glucose transporter member 4; Insulin-regulated facilitative glucose transporter, which plays a key role in removal of glucose from circulation. Response to insulin is regulated by its intracellular localization: in the absence of insulin, it is efficiently retained intracellularly within storage compartments in muscle and fat cells. Upon insulin stimulation, translocates from these compartments to the cell surface where it transports glucose from the extracellular milieu into the cell.
   
  
 0.534
PRPSAP2
Phosphoribosyl pyrophosphate synthetase associated protein 2; Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.
      
 0.515
LDHA
L-lactate dehydrogenase; Belongs to the LDH/MDH superfamily.
   
  
 0.507
PFKP
Phosphofructokinase, platelet.
   
  
 0.488
EMB
Embigin.
    
 
 0.474
Your Current Organism:
Canis lupus familiaris
NCBI taxonomy Id: 9615
Other names: C. lupus familiaris, Canis canis, Canis domesticus, Canis familiaris, beagle dog, beagle dogs, dog, dogs
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.