PRND protein (Canis lupus familiaris) - STRING interaction network

Nodes:

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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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[Homology]

Score

PRND

Prion like protein doppel. (178 aa)

Predicted Functional Partners:

PRNP

0.766

MAPK15

0.733

SUOX

0.615

TMCO2

0.604

NEGR1

0.604

SPRN

0.597

MMP19

0.595

SPATA6

0.594

XKR7

0.591

FAM177B

0.591

Your Current Organism:

Canis lupus familiaris

NCBI taxonomy Id: 9615
Other names: C. lupus familiaris, Canis canis, Canis domesticus, Canis familiaris, beagle dog, beagle dogs, dog, dogs

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... protein annotations:

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a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
FAM177B	NEGR1	ENSCAFP00000019898	ENSCAFP00000030275	Family with sequence similarity 177 member B.	Neuronal growth regulator 1.	0.427
FAM177B	PRND	ENSCAFP00000019898	ENSCAFP00000009105	Family with sequence similarity 177 member B.	Prion like protein doppel.	0.591
FAM177B	XKR7	ENSCAFP00000019898	ENSCAFP00000010553	Family with sequence similarity 177 member B.	XK-related protein.	0.591
MAPK15	PRND	ENSCAFP00000044900	ENSCAFP00000009105	Mitogen-activated protein kinase.	Prion like protein doppel.	0.733
MMP19	NEGR1	ENSCAFP00000000111	ENSCAFP00000030275	Matrix metallopeptidase 19.	Neuronal growth regulator 1.	0.487
MMP19	PRND	ENSCAFP00000000111	ENSCAFP00000009105	Matrix metallopeptidase 19.	Prion like protein doppel.	0.595
MMP19	SPATA6	ENSCAFP00000000111	ENSCAFP00000005868	Matrix metallopeptidase 19.	Spermatogenesis associated 6.	0.600
MMP19	SUOX	ENSCAFP00000000111	ENSCAFP00000065414	Matrix metallopeptidase 19.	Sulfite oxidase.	0.487
NEGR1	FAM177B	ENSCAFP00000030275	ENSCAFP00000019898	Neuronal growth regulator 1.	Family with sequence similarity 177 member B.	0.427
NEGR1	MMP19	ENSCAFP00000030275	ENSCAFP00000000111	Neuronal growth regulator 1.	Matrix metallopeptidase 19.	0.487
NEGR1	PRND	ENSCAFP00000030275	ENSCAFP00000009105	Neuronal growth regulator 1.	Prion like protein doppel.	0.604
NEGR1	PRNP	ENSCAFP00000030275	ENSCAFP00000009107	Neuronal growth regulator 1.	Major prion protein; Its primary physiological function is unclear. May play a role in neuronal development and synaptic plasticity. May be required for neuronal myelin sheath maintenance. May promote myelin homeostasis through acting as an agonist for ADGRG6 receptor. May play a role in iron uptake and iron homeostasis. Soluble oligomers are toxic to cultured neuroblastoma cells and induce apoptosis (in vitro) (By similarity). Association with GPC1 (via its heparan sulfate chains) targets PRNP to lipid rafts. Also provides Cu(2+) or ZN(2+) for the ascorbate-mediated GPC1 deaminase deg [...]	0.584
NEGR1	SPATA6	ENSCAFP00000030275	ENSCAFP00000005868	Neuronal growth regulator 1.	Spermatogenesis associated 6.	0.483
NEGR1	XKR7	ENSCAFP00000030275	ENSCAFP00000010553	Neuronal growth regulator 1.	XK-related protein.	0.463
PRND	FAM177B	ENSCAFP00000009105	ENSCAFP00000019898	Prion like protein doppel.	Family with sequence similarity 177 member B.	0.591
PRND	MAPK15	ENSCAFP00000009105	ENSCAFP00000044900	Prion like protein doppel.	Mitogen-activated protein kinase.	0.733
PRND	MMP19	ENSCAFP00000009105	ENSCAFP00000000111	Prion like protein doppel.	Matrix metallopeptidase 19.	0.595
PRND	NEGR1	ENSCAFP00000009105	ENSCAFP00000030275	Prion like protein doppel.	Neuronal growth regulator 1.	0.604
PRND	PRNP	ENSCAFP00000009105	ENSCAFP00000009107	Prion like protein doppel.	Major prion protein; Its primary physiological function is unclear. May play a role in neuronal development and synaptic plasticity. May be required for neuronal myelin sheath maintenance. May promote myelin homeostasis through acting as an agonist for ADGRG6 receptor. May play a role in iron uptake and iron homeostasis. Soluble oligomers are toxic to cultured neuroblastoma cells and induce apoptosis (in vitro) (By similarity). Association with GPC1 (via its heparan sulfate chains) targets PRNP to lipid rafts. Also provides Cu(2+) or ZN(2+) for the ascorbate-mediated GPC1 deaminase deg [...]	0.766
PRND	SPATA6	ENSCAFP00000009105	ENSCAFP00000005868	Prion like protein doppel.	Spermatogenesis associated 6.	0.594