STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
COL4A1Collagen type IV alpha 1 chain. (1586 aa)    
Predicted Functional Partners:
COL4A2
Collagen type IV alpha 2 chain.
  
 
0.963
GP6
Glycoprotein VI platelet.
   
 
 0.907
PELO
Integrin subunit alpha 1; Belongs to the integrin alpha chain family.
   
 0.787
ITGA5
Integrin subunit alpha 5; Belongs to the integrin alpha chain family.
   
 0.749
ITGA11
Integrin subunit alpha 11; Belongs to the integrin alpha chain family.
   
 0.748
ITGB1
Integrin beta; Belongs to the integrin beta chain family.
   
 0.747
ITGA6
Integrin subunit alpha 6; Belongs to the integrin alpha chain family.
   
 0.744
ITGAV
Integrin subunit alpha V; Belongs to the integrin alpha chain family.
   
 0.732
PTK2
Protein tyrosine kinase 2; Belongs to the protein kinase superfamily. Tyr protein kinase family.
   
 
 0.727
ITGA8
Integrin subunit alpha 8; Belongs to the integrin alpha chain family.
   
 0.717
Your Current Organism:
Canis lupus familiaris
NCBI taxonomy Id: 9615
Other names: C. lupus familiaris, Canis canis, Canis domesticus, Canis familiaris, beagle dog, beagle dogs, dog, dogs
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.