STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
COL4A2Collagen type IV alpha 2 chain. (329 aa)    
Predicted Functional Partners:
COL4A1
Collagen type IV alpha 1 chain.
  
 
0.963
COL4A3
Collagen type IV alpha 3 chain.
  
 
0.936
COL4A5
Collagen alpha-5(IV) chain; Type IV collagen is the major structural component of glomerular basement membranes (GBM), forming a 'chicken-wire' meshwork together with laminins, proteoglycans and entactin/nidogen.
  
 
0.934
GP6
Glycoprotein VI platelet.
     
 0.902
PELO
Integrin subunit alpha 1; Belongs to the integrin alpha chain family.
   
 0.878
ITGB4
Integrin beta.
   
 0.771
ITGAV
Integrin subunit alpha V; Belongs to the integrin alpha chain family.
    
 0.770
ITGA6
Integrin subunit alpha 6; Belongs to the integrin alpha chain family.
   
 0.752
ITGA10
Integrin subunit alpha 10; Belongs to the integrin alpha chain family.
   
 0.744
ITGB1
Integrin beta; Belongs to the integrin beta chain family.
   
 0.737
Your Current Organism:
Canis lupus familiaris
NCBI taxonomy Id: 9615
Other names: C. lupus familiaris, Canis canis, Canis domesticus, Canis familiaris, beagle dog, beagle dogs, dog, dogs
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.