CHFR protein (Canis lupus familiaris) - STRING interaction network

Nodes:

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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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query proteins and first shell of interactors

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second shell of interactors

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proteins of unknown 3D structure

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a 3D structure is known or predicted

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Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

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experimentally determined

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[Homology]

Score

CHFR

Checkpoint with forkhead and ring finger domains. (726 aa)

Predicted Functional Partners:

PARP1

0.941

PLK1

0.814

UBE2D1

0.811

APLF

0.772

PARP2

0.740

USP7

0.720

PARP3

0.700

HLTF

0.617

TBRG1

0.610

GOLGA3

0.603

Your Current Organism:

Canis lupus familiaris

NCBI taxonomy Id: 9615
Other names: C. lupus familiaris, Canis canis, Canis domesticus, Canis familiaris, beagle dog, beagle dogs, dog, dogs

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structured XML interaction data, according to the 'PSI-MI' data standard

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... protein annotations:

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a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

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a tab-delimited file containing all known functional terms of proteins in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
APLF	CHFR	ENSCAFP00000004843	ENSCAFP00000009126	Aprataxin and PNKP like factor.	Checkpoint with forkhead and ring finger domains.	0.772
APLF	HLTF	ENSCAFP00000004843	ENSCAFP00000012193	Aprataxin and PNKP like factor.	Helicase like transcription factor.	0.849
APLF	PARP1	ENSCAFP00000004843	ENSCAFP00000023715	Aprataxin and PNKP like factor.	Poly [ADP-ribose] polymerase; Poly-ADP-ribosyltransferase that mediates poly-ADP- ribosylation of proteins and plays a key role in DNA repair.	0.958
APLF	PARP2	ENSCAFP00000004843	ENSCAFP00000059353	Aprataxin and PNKP like factor.	Poly [ADP-ribose] polymerase.	0.918
APLF	PARP3	ENSCAFP00000004843	ENSCAFP00000014771	Aprataxin and PNKP like factor.	Poly [ADP-ribose] polymerase.	0.818
CHFR	APLF	ENSCAFP00000009126	ENSCAFP00000004843	Checkpoint with forkhead and ring finger domains.	Aprataxin and PNKP like factor.	0.772
CHFR	GOLGA3	ENSCAFP00000009126	ENSCAFP00000009144	Checkpoint with forkhead and ring finger domains.	Golgin A3.	0.603
CHFR	HLTF	ENSCAFP00000009126	ENSCAFP00000012193	Checkpoint with forkhead and ring finger domains.	Helicase like transcription factor.	0.617
CHFR	PARP1	ENSCAFP00000009126	ENSCAFP00000023715	Checkpoint with forkhead and ring finger domains.	Poly [ADP-ribose] polymerase; Poly-ADP-ribosyltransferase that mediates poly-ADP- ribosylation of proteins and plays a key role in DNA repair.	0.941
CHFR	PARP2	ENSCAFP00000009126	ENSCAFP00000059353	Checkpoint with forkhead and ring finger domains.	Poly [ADP-ribose] polymerase.	0.740
CHFR	PARP3	ENSCAFP00000009126	ENSCAFP00000014771	Checkpoint with forkhead and ring finger domains.	Poly [ADP-ribose] polymerase.	0.700
CHFR	PLK1	ENSCAFP00000009126	ENSCAFP00000039127	Checkpoint with forkhead and ring finger domains.	Serine/threonine-protein kinase PLK.	0.814
CHFR	TBRG1	ENSCAFP00000009126	ENSCAFP00000016504	Checkpoint with forkhead and ring finger domains.	Transforming growth factor beta regulator 1.	0.610
CHFR	UBE2D1	ENSCAFP00000009126	ENSCAFP00000036387	Checkpoint with forkhead and ring finger domains.	Ubiquitin conjugating enzyme E2 D1; Belongs to the ubiquitin-conjugating enzyme family.	0.811
CHFR	USP7	ENSCAFP00000009126	ENSCAFP00000028037	Checkpoint with forkhead and ring finger domains.	Ubiquitin specific peptidase 7; Belongs to the peptidase C19 family.	0.720
GOLGA3	CHFR	ENSCAFP00000009144	ENSCAFP00000009126	Golgin A3.	Checkpoint with forkhead and ring finger domains.	0.603
HLTF	APLF	ENSCAFP00000012193	ENSCAFP00000004843	Helicase like transcription factor.	Aprataxin and PNKP like factor.	0.849
HLTF	CHFR	ENSCAFP00000012193	ENSCAFP00000009126	Helicase like transcription factor.	Checkpoint with forkhead and ring finger domains.	0.617
HLTF	PARP1	ENSCAFP00000012193	ENSCAFP00000023715	Helicase like transcription factor.	Poly [ADP-ribose] polymerase; Poly-ADP-ribosyltransferase that mediates poly-ADP- ribosylation of proteins and plays a key role in DNA repair.	0.447
PARP1	APLF	ENSCAFP00000023715	ENSCAFP00000004843	Poly [ADP-ribose] polymerase; Poly-ADP-ribosyltransferase that mediates poly-ADP- ribosylation of proteins and plays a key role in DNA repair.	Aprataxin and PNKP like factor.	0.958