Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
DDHD2DDHD domain containing 2. (715 aa)    
Predicted Functional Partners:
DDHD1
DDHD domain containing 1.
     
0.919
TM2D2
TM2 domain containing 2.
   
  
 0.818
MCOLN1
Patatin like phospholipase domain containing 6.
   
  
 0.697
SPART
Spartin.
      
 0.673
SPG21
SPG21 abhydrolase domain containing, maspardin.
   
  
 0.643
ERLIN2
ER lipid raft associated 2.
   
  
 0.638
GJC2
Gap junction protein; One gap junction consists of a cluster of closely packed pairs of transmembrane channels, the connexons, through which materials of low MW diffuse from one cell to a neighboring cell.
      
 0.638
FBXO22
Ubiquitin conjugating enzyme E2 Q2.
   
  
 0.627
NIPA1
NIPA magnesium transporter 1.
      
 0.609
ZFYVE26
Zinc finger FYVE-type containing 26.
   
 
 0.608
Your Current Organism:
Canis lupus familiaris
NCBI taxonomy Id: 9615
Other names: C. lupus familiaris, Canis canis, Canis domesticus, Canis familiaris, beagle dog, beagle dogs, dog, dogs
Server load: medium (44%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.