STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
RNF24Ring finger protein 24. (148 aa)    
Predicted Functional Partners:
PANK2
Pantothenate kinase 2.
   
  
 0.866
PCED1A
PC-esterase domain containing 1A.
      
 0.820
VPS16
Vacuolar protein sorting-associated protein 16 homolog; Plays a role in vesicle-mediated protein trafficking to lysosomal compartments including the endocytic membrane transport and autophagic pathways. Believed to act as a core component of the putative HOPS and CORVET endosomal tethering complexes. Belongs to the VPS16 family.
      
 0.812
POF1B
POF1B actin binding protein.
      
 0.812
ZNF711
Zinc finger protein 711.
    
 
 0.808
PTPRA
Receptor-type tyrosine-protein phosphatase alpha.
   
 
 0.705
MARCHF2
Membrane associated ring-CH-type finger 2.
    
 
 0.687
CLRN3
Clarin 3.
      
 0.649
GMDS
GDP-mannose 4,6-dehydratase.
      
 0.647
PSMA8
Proteasome subunit alpha type.
    
 
 0.608
Your Current Organism:
Canis lupus familiaris
NCBI taxonomy Id: 9615
Other names: C. lupus familiaris, Canis canis, Canis domesticus, Canis familiaris, beagle dog, beagle dogs, dog, dogs
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