STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
SEMA3DSemaphorin 3D; Belongs to the semaphorin family. (777 aa)    
Predicted Functional Partners:
NRP1
Neuropilin 1.
   
 0.971
PLXND1
Plexin D1.
   
 
 0.808
CPNE4
Copine 4.
   
  
 0.672
TMEM117
Transmembrane protein 117.
      
 0.672
SLC2A13
Solute carrier family 2 member 13; Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family.
      
 0.672
PLXNA3
Plexin A3.
    
 
 0.656
TCTN1
Tectonic family member 1.
      
 0.646
TMEM161B
Transmembrane protein 161B.
      
 0.608
KBTBD12
Kelch repeat and BTB domain containing 12.
   
  
 0.602
NAALADL2
N-acetylated alpha-linked acidic dipeptidase like 2.
   
  
 0.595
Your Current Organism:
Canis lupus familiaris
NCBI taxonomy Id: 9615
Other names: C. lupus familiaris, Canis canis, Canis domesticus, Canis familiaris, beagle dog, beagle dogs, dog, dogs
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