STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
SPARTSpartin. (750 aa)    
Predicted Functional Partners:
IST1
IST1 factor associated with ESCRT-III.
    
 
 0.893
NIPA1
NIPA magnesium transporter 1.
   
  
 0.782
WWP1
E3 ubiquitin-protein ligase.
    
 
 0.765
ATL1
Atlastin GTPase 1.
      
 0.762
SPG11
SPG11 vesicle trafficking associated, spatacsin.
      
 0.748
ATL2
Atlastin GTPase 2.
      
 0.743
ATL3
Atlastin GTPase 3.
      
 0.741
SPG21
SPG21 abhydrolase domain containing, maspardin.
      
 0.736
BSCL2
BSCL2 lipid droplet biogenesis associated, seipin.
      
 0.720
DDHD2
DDHD domain containing 2.
      
 0.681
Your Current Organism:
Canis lupus familiaris
NCBI taxonomy Id: 9615
Other names: C. lupus familiaris, Canis canis, Canis domesticus, Canis familiaris, beagle dog, beagle dogs, dog, dogs
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.