STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
SPARTSpartin. (750 aa)    
Predicted Functional Partners:
ITCH
E3 ubiquitin-protein ligase.
    
 
 0.937
IST1
IST1 factor associated with ESCRT-III.
    
 
 0.904
WWP1
E3 ubiquitin-protein ligase.
    
 
 0.889
ATL1
Atlastin GTPase 1.
      
 0.790
ATL3
Atlastin GTPase 3.
      
 0.786
NIPA1
NIPA magnesium transporter 1.
      
 0.783
ATL2
Atlastin GTPase 2.
      
 0.782
SPG11
SPG11 vesicle trafficking associated, spatacsin.
      
 0.754
SPG21
SPG21 abhydrolase domain containing, maspardin.
      
 0.751
WWP2
E3 ubiquitin-protein ligase.
    
 
 0.716
Your Current Organism:
Canis lupus familiaris
NCBI taxonomy Id: 9615
Other names: C. lupus familiaris, Canis canis, Canis domesticus, Canis familiaris, beagle dog, beagle dogs, dog, dogs
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.