DELE1 protein (Canis lupus familiaris) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:

Neighborhood

Gene Fusion

Cooccurrence

Coexpression

Experiments

Databases

Textmining

[Homology]

Score

DELE1

DAP3 binding cell death enhancer 1. (521 aa)

Predicted Functional Partners:

TK2

0.660

OS9

0.599

ERLEC1

0.599

EIF2AK1

0.576

ADAR

0.565

OMA1

0.549

HAS1

0.527

HAS3

0.527

HAS2

0.527

EIF2A

0.522

Your Current Organism:

Canis lupus familiaris

NCBI taxonomy Id: 9615
Other names: C. lupus familiaris, Canis canis, Canis domesticus, Canis familiaris, beagle dog, beagle dogs, dog, dogs

Send network to Cytoscape

Export your current network:

... as a bitmap image:

download

file format is 'PNG': portable network graphic

... as a high-resolution bitmap:

download

same PNG format, but at higher resolution

... as a vector graphic:

download

SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc

... as short tabular text output:

download

TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)

... as tabular text output:

download

TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)

... as an XML summary:

download

structured XML interaction data, according to the 'PSI-MI' data standard

... protein node degrees:

download

node degree of proteins in your network (given the current score cut-off)

... network coordinates:

download

a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

download

MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

download

a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

download

a tab-delimited file containing all known functional terms of proteins in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ADAR	DELE1	ENSCAFP00000025289	ENSCAFP00000009343	Adenosine deaminase RNA specific.	DAP3 binding cell death enhancer 1.	0.565
DELE1	ADAR	ENSCAFP00000009343	ENSCAFP00000025289	DAP3 binding cell death enhancer 1.	Adenosine deaminase RNA specific.	0.565
DELE1	EIF2A	ENSCAFP00000009343	ENSCAFP00000012365	DAP3 binding cell death enhancer 1.	Eukaryotic translation initiation factor 2A; Functions in the early steps of protein synthesis of a small number of specific mRNAs. Acts by directing the binding of methionyl- tRNAi to 40S ribosomal subunits. In contrast to the eIF-2 complex, it binds methionyl-tRNAi to 40S subunits in a codon-dependent manner, whereas the eIF-2 complex binds methionyl-tRNAi to 40S subunits in a GTP-dependent manner.	0.522
DELE1	EIF2AK1	ENSCAFP00000009343	ENSCAFP00000023026	DAP3 binding cell death enhancer 1.	Eukaryotic translation initiation factor 2 alpha kinase 1.	0.576
DELE1	ERLEC1	ENSCAFP00000009343	ENSCAFP00000047976	DAP3 binding cell death enhancer 1.	Endoplasmic reticulum lectin 1.	0.599
DELE1	HAS1	ENSCAFP00000009343	ENSCAFP00000004163	DAP3 binding cell death enhancer 1.	Hyaluronan synthase 1.	0.527
DELE1	HAS2	ENSCAFP00000009343	ENSCAFP00000042994	DAP3 binding cell death enhancer 1.	Hyaluronan synthase 2.	0.527
DELE1	HAS3	ENSCAFP00000009343	ENSCAFP00000030096	DAP3 binding cell death enhancer 1.	Hyaluronan synthase 3.	0.527
DELE1	OMA1	ENSCAFP00000009343	ENSCAFP00000027897	DAP3 binding cell death enhancer 1.	OMA1 zinc metallopeptidase.	0.549
DELE1	OS9	ENSCAFP00000009343	ENSCAFP00000000376	DAP3 binding cell death enhancer 1.	OS9 endoplasmic reticulum lectin.	0.599
DELE1	TK2	ENSCAFP00000009343	ENSCAFP00000030286	DAP3 binding cell death enhancer 1.	Thymidine kinase 2.	0.660
EIF2A	DELE1	ENSCAFP00000012365	ENSCAFP00000009343	Eukaryotic translation initiation factor 2A; Functions in the early steps of protein synthesis of a small number of specific mRNAs. Acts by directing the binding of methionyl- tRNAi to 40S ribosomal subunits. In contrast to the eIF-2 complex, it binds methionyl-tRNAi to 40S subunits in a codon-dependent manner, whereas the eIF-2 complex binds methionyl-tRNAi to 40S subunits in a GTP-dependent manner.	DAP3 binding cell death enhancer 1.	0.522
EIF2A	EIF2AK1	ENSCAFP00000012365	ENSCAFP00000023026	Eukaryotic translation initiation factor 2A; Functions in the early steps of protein synthesis of a small number of specific mRNAs. Acts by directing the binding of methionyl- tRNAi to 40S ribosomal subunits. In contrast to the eIF-2 complex, it binds methionyl-tRNAi to 40S subunits in a codon-dependent manner, whereas the eIF-2 complex binds methionyl-tRNAi to 40S subunits in a GTP-dependent manner.	Eukaryotic translation initiation factor 2 alpha kinase 1.	0.432
EIF2AK1	DELE1	ENSCAFP00000023026	ENSCAFP00000009343	Eukaryotic translation initiation factor 2 alpha kinase 1.	DAP3 binding cell death enhancer 1.	0.576
EIF2AK1	EIF2A	ENSCAFP00000023026	ENSCAFP00000012365	Eukaryotic translation initiation factor 2 alpha kinase 1.	Eukaryotic translation initiation factor 2A; Functions in the early steps of protein synthesis of a small number of specific mRNAs. Acts by directing the binding of methionyl- tRNAi to 40S ribosomal subunits. In contrast to the eIF-2 complex, it binds methionyl-tRNAi to 40S subunits in a codon-dependent manner, whereas the eIF-2 complex binds methionyl-tRNAi to 40S subunits in a GTP-dependent manner.	0.432
ERLEC1	DELE1	ENSCAFP00000047976	ENSCAFP00000009343	Endoplasmic reticulum lectin 1.	DAP3 binding cell death enhancer 1.	0.599
ERLEC1	OS9	ENSCAFP00000047976	ENSCAFP00000000376	Endoplasmic reticulum lectin 1.	OS9 endoplasmic reticulum lectin.	0.748
HAS1	DELE1	ENSCAFP00000004163	ENSCAFP00000009343	Hyaluronan synthase 1.	DAP3 binding cell death enhancer 1.	0.527
HAS2	DELE1	ENSCAFP00000042994	ENSCAFP00000009343	Hyaluronan synthase 2.	DAP3 binding cell death enhancer 1.	0.527
HAS3	DELE1	ENSCAFP00000030096	ENSCAFP00000009343	Hyaluronan synthase 3.	DAP3 binding cell death enhancer 1.	0.527