STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
DELE1DAP3 binding cell death enhancer 1. (521 aa)    
Predicted Functional Partners:
EIF2AK1
Eukaryotic translation initiation factor 2 alpha kinase 1.
    
 0.959
OMA1
OMA1 zinc metallopeptidase.
  
 
 0.945
STOML2
Stomatin like 2.
   
 0.767
HAS1
Hyaluronan synthase 1.
  
 0.624
HAS3
Hyaluronan synthase 3.
  
 0.624
HAS2
Hyaluronan synthase 2.
  
 0.624
EIF2S1
Eukaryotic translation initiation factor 2 subunit alpha.
     
 0.572
TK2
Thymidine kinase 2.
      
 0.531
DAP3
Death associated protein 3.
      
 0.530
LONP1
Lon protease homolog, mitochondrial; ATP-dependent serine protease that mediates the selective degradation of misfolded, unassembled or oxidatively damaged polypeptides as well as certain short-lived regulatory proteins in the mitochondrial matrix. May also have a chaperone function in the assembly of inner membrane protein complexes. Participates in the regulation of mitochondrial gene expression and in the maintenance of the integrity of the mitochondrial genome. Binds to mitochondrial promoters and RNA in a single-stranded, site-specific, and strand- specific manner. May regulate mi [...]
   
  
 0.521
Your Current Organism:
Canis lupus familiaris
NCBI taxonomy Id: 9615
Other names: C. lupus familiaris, Canis canis, Canis domesticus, Canis familiaris, beagle dog, beagle dogs, dog, dogs
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