STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
ADAM33ADAM metallopeptidase domain 33. (875 aa)    
Predicted Functional Partners:
DPP10
Dipeptidyl peptidase like 10; Belongs to the peptidase S9B family.
   
  
 0.791
ORMDL3
ORM1-like protein; Negative regulator of sphingolipid synthesis.
      
 0.777
ADAMTSL5
ADAMTS like 5.
      
 0.612
MRPL4
Mitochondrial ribosomal protein L4.
      
 0.591
SLC30A2
Solute carrier family 30 member 2.
    
   0.570
CNOT6
CCR4-NOT transcription complex subunit 6.
      
 0.517
NPSR1
Neuropeptide S receptor 1; Belongs to the G-protein coupled receptor 1 family. Vasopressin/oxytocin receptor subfamily.
   
  
 0.517
IL4R
Interleukin 4 receptor.
   
 0.512
IL1RL1
Interleukin 1 receptor like 1.
      
 0.490
FCER1A
Fc fragment of IgE receptor Ia.
      
 0.484
Your Current Organism:
Canis lupus familiaris
NCBI taxonomy Id: 9615
Other names: C. lupus familiaris, Canis canis, Canis domesticus, Canis familiaris, beagle dog, beagle dogs, dog, dogs
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.