STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
GFRA4GDNF family receptor alpha 4. (274 aa)    
Predicted Functional Partners:
PSPN
Persephin.
    
 0.954
RET
Ret proto-oncogene; Belongs to the protein kinase superfamily. Tyr protein kinase family.
     
 0.945
J9P9V2_CANLF
Uncharacterized protein.
      
 0.692
NRTN
Neurturin.
   
 
 0.688
GDNF
Glial cell derived neurotrophic factor.
     
 0.576
SLC7A10
Solute carrier family 7 member 10.
      
 0.574
OVCH2
Ovochymase 2; Belongs to the peptidase S1 family.
      
 0.528
OVCH1
Uncharacterized protein; Belongs to the peptidase S1 family.
      
 0.528
NCAN
Neurocan.
      
 0.519
SRC
Tyrosine-protein kinase.
   
 
  0.512
Your Current Organism:
Canis lupus familiaris
NCBI taxonomy Id: 9615
Other names: C. lupus familiaris, Canis canis, Canis domesticus, Canis familiaris, beagle dog, beagle dogs, dog, dogs
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.