NR2C1 protein (Canis lupus familiaris) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Knowledge-based Evidence

from curated databases

textmining

Assay-based Predictions

experimentally determined

co-expression

Genomic Predictions

gene neighborhood

gene co-occurrence

gene fusions

Your Input:

Neighborhood

Gene Fusion

Cooccurrence

Coexpression

Experiments

Databases

Textmining

[Homology]

Score

NR2C1

Nuclear receptor subfamily 2 group C member 1. (605 aa)

Predicted Functional Partners:

NRIP1

0.898

HDAC3

0.867

FKBP9

0.764

PML

0.688

ZNF276

0.675

ZBTB48

0.655

ZNF827

0.649

NAIF1

0.645

DCLRE1B

0.644

SRBD1

0.640

Your Current Organism:

Canis lupus familiaris

NCBI taxonomy Id: 9615
Other names: C. lupus familiaris, Canis canis, Canis domesticus, Canis familiaris, beagle dog, beagle dogs, dog, dogs

Export your current network:

... as a bitmap image:

download

file format is 'PNG': portable network graphic

... as a high-resolution bitmap:

download

same PNG format, but at higher resolution

... as a vector graphic:

download

SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc

... as short tabular text output:

download

TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)

... as tabular text output:

download

TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)

... as an XML summary:

download

structured XML interaction data, according to the 'PSI-MI' data standard

... protein node degrees:

download

node degree of proteins in your network (given the current score cut-off)

... network coordinates:

download

a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

download

MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

download

a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

download

a tab-delimited file containing all known functional terms of proteins in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
DCLRE1B	NAIF1	ENSCAFP00000013629	ENSCAFP00000029781	DNA cross-link repair 1B.	Nuclear apoptosis inducing factor 1.	0.770
DCLRE1B	NR2C1	ENSCAFP00000013629	ENSCAFP00000009377	DNA cross-link repair 1B.	Nuclear receptor subfamily 2 group C member 1.	0.644
DCLRE1B	SRBD1	ENSCAFP00000013629	ENSCAFP00000003722	DNA cross-link repair 1B.	S1 RNA binding domain 1.	0.734
DCLRE1B	ZBTB48	ENSCAFP00000013629	ENSCAFP00000029010	DNA cross-link repair 1B.	Zinc finger and BTB domain containing 48.	0.750
DCLRE1B	ZNF276	ENSCAFP00000013629	ENSCAFP00000056766	DNA cross-link repair 1B.	Zinc finger protein 276.	0.800
DCLRE1B	ZNF827	ENSCAFP00000013629	ENSCAFP00000047563	DNA cross-link repair 1B.	Zinc finger protein 827.	0.771
FKBP9	NR2C1	ENSCAFP00000004699	ENSCAFP00000009377	Peptidylprolyl isomerase.	Nuclear receptor subfamily 2 group C member 1.	0.764
HDAC3	NR2C1	ENSCAFP00000030390	ENSCAFP00000009377	Histone deacetylase 3; Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4), and some other non-histone substrates. Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. Histone deacetylases act via the formation of large multiprotein complexes.	Nuclear receptor subfamily 2 group C member 1.	0.867
HDAC3	NRIP1	ENSCAFP00000030390	ENSCAFP00000011935	Histone deacetylase 3; Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4), and some other non-histone substrates. Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. Histone deacetylases act via the formation of large multiprotein complexes.	Nuclear receptor interacting protein 1.	0.606
NAIF1	DCLRE1B	ENSCAFP00000029781	ENSCAFP00000013629	Nuclear apoptosis inducing factor 1.	DNA cross-link repair 1B.	0.770
NAIF1	NR2C1	ENSCAFP00000029781	ENSCAFP00000009377	Nuclear apoptosis inducing factor 1.	Nuclear receptor subfamily 2 group C member 1.	0.645
NAIF1	SRBD1	ENSCAFP00000029781	ENSCAFP00000003722	Nuclear apoptosis inducing factor 1.	S1 RNA binding domain 1.	0.743
NAIF1	ZBTB48	ENSCAFP00000029781	ENSCAFP00000029010	Nuclear apoptosis inducing factor 1.	Zinc finger and BTB domain containing 48.	0.754
NAIF1	ZNF276	ENSCAFP00000029781	ENSCAFP00000056766	Nuclear apoptosis inducing factor 1.	Zinc finger protein 276.	0.807
NAIF1	ZNF827	ENSCAFP00000029781	ENSCAFP00000047563	Nuclear apoptosis inducing factor 1.	Zinc finger protein 827.	0.749
NR2C1	DCLRE1B	ENSCAFP00000009377	ENSCAFP00000013629	Nuclear receptor subfamily 2 group C member 1.	DNA cross-link repair 1B.	0.644
NR2C1	FKBP9	ENSCAFP00000009377	ENSCAFP00000004699	Nuclear receptor subfamily 2 group C member 1.	Peptidylprolyl isomerase.	0.764
NR2C1	HDAC3	ENSCAFP00000009377	ENSCAFP00000030390	Nuclear receptor subfamily 2 group C member 1.	Histone deacetylase 3; Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4), and some other non-histone substrates. Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. Histone deacetylases act via the formation of large multiprotein complexes.	0.867
NR2C1	NAIF1	ENSCAFP00000009377	ENSCAFP00000029781	Nuclear receptor subfamily 2 group C member 1.	Nuclear apoptosis inducing factor 1.	0.645
NR2C1	NRIP1	ENSCAFP00000009377	ENSCAFP00000011935	Nuclear receptor subfamily 2 group C member 1.	Nuclear receptor interacting protein 1.	0.898