P2RX2 protein (Canis lupus familiaris) - STRING interaction network

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Score

P2RX2

P2X purinoceptor; Receptor for ATP that acts as a ligand-gated ion channel. (463 aa)

Predicted Functional Partners:

P2RX3

0.930

P2RX6

0.927

P2RX5

0.912

P2RX7

0.911

P2RX1

0.910

P2RX4

0.854

GRIN3A

0.807

GRIN2D

0.803

GRIN2A

0.799

GRIN1

0.799

Your Current Organism:

Canis lupus familiaris

NCBI taxonomy Id: 9615
Other names: C. lupus familiaris, Canis canis, Canis domesticus, Canis familiaris, beagle dog, beagle dogs, dog, dogs

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
GRIN1	GRIN2A	ENSCAFP00000037473	ENSCAFP00000028005	Glutamate receptor ionotropic, NMDA 1; Component of NMDA receptor complexes that function as heterotetrameric, ligand-gated ion channels with high calcium permeability and voltage-dependent sensitivity to magnesium. Channel activation requires binding of the neurotransmitter glutamate to the epsilon subunit, glycine binding to the zeta subunit, plus membrane depolarization to eliminate channel inhibition by Mg(2+). Sensitivity to glutamate and channel kinetics depend on the subunit composition. Belongs to the glutamate-gated ion channel (TC 1.A.10.1) family. NR1/GRIN1 subfamily.	Glutamate ionotropic receptor NMDA type subunit 2A.	0.999
GRIN1	GRIN2D	ENSCAFP00000037473	ENSCAFP00000061970	Glutamate receptor ionotropic, NMDA 1; Component of NMDA receptor complexes that function as heterotetrameric, ligand-gated ion channels with high calcium permeability and voltage-dependent sensitivity to magnesium. Channel activation requires binding of the neurotransmitter glutamate to the epsilon subunit, glycine binding to the zeta subunit, plus membrane depolarization to eliminate channel inhibition by Mg(2+). Sensitivity to glutamate and channel kinetics depend on the subunit composition. Belongs to the glutamate-gated ion channel (TC 1.A.10.1) family. NR1/GRIN1 subfamily.	Glutamate ionotropic receptor NMDA type subunit 2D; Belongs to the glutamate-gated ion channel (TC 1.A.10.1) family.	0.997
GRIN1	GRIN3A	ENSCAFP00000037473	ENSCAFP00000003807	Glutamate receptor ionotropic, NMDA 1; Component of NMDA receptor complexes that function as heterotetrameric, ligand-gated ion channels with high calcium permeability and voltage-dependent sensitivity to magnesium. Channel activation requires binding of the neurotransmitter glutamate to the epsilon subunit, glycine binding to the zeta subunit, plus membrane depolarization to eliminate channel inhibition by Mg(2+). Sensitivity to glutamate and channel kinetics depend on the subunit composition. Belongs to the glutamate-gated ion channel (TC 1.A.10.1) family. NR1/GRIN1 subfamily.	Glutamate ionotropic receptor NMDA type subunit 3A.	0.990
GRIN1	P2RX1	ENSCAFP00000037473	ENSCAFP00000028598	Glutamate receptor ionotropic, NMDA 1; Component of NMDA receptor complexes that function as heterotetrameric, ligand-gated ion channels with high calcium permeability and voltage-dependent sensitivity to magnesium. Channel activation requires binding of the neurotransmitter glutamate to the epsilon subunit, glycine binding to the zeta subunit, plus membrane depolarization to eliminate channel inhibition by Mg(2+). Sensitivity to glutamate and channel kinetics depend on the subunit composition. Belongs to the glutamate-gated ion channel (TC 1.A.10.1) family. NR1/GRIN1 subfamily.	P2X purinoceptor; Receptor for ATP that acts as a ligand-gated ion channel.	0.798
GRIN1	P2RX2	ENSCAFP00000037473	ENSCAFP00000009417	Glutamate receptor ionotropic, NMDA 1; Component of NMDA receptor complexes that function as heterotetrameric, ligand-gated ion channels with high calcium permeability and voltage-dependent sensitivity to magnesium. Channel activation requires binding of the neurotransmitter glutamate to the epsilon subunit, glycine binding to the zeta subunit, plus membrane depolarization to eliminate channel inhibition by Mg(2+). Sensitivity to glutamate and channel kinetics depend on the subunit composition. Belongs to the glutamate-gated ion channel (TC 1.A.10.1) family. NR1/GRIN1 subfamily.	P2X purinoceptor; Receptor for ATP that acts as a ligand-gated ion channel.	0.799
GRIN1	P2RX3	ENSCAFP00000037473	ENSCAFP00000066381	Glutamate receptor ionotropic, NMDA 1; Component of NMDA receptor complexes that function as heterotetrameric, ligand-gated ion channels with high calcium permeability and voltage-dependent sensitivity to magnesium. Channel activation requires binding of the neurotransmitter glutamate to the epsilon subunit, glycine binding to the zeta subunit, plus membrane depolarization to eliminate channel inhibition by Mg(2+). Sensitivity to glutamate and channel kinetics depend on the subunit composition. Belongs to the glutamate-gated ion channel (TC 1.A.10.1) family. NR1/GRIN1 subfamily.	P2X purinoceptor; Receptor for ATP that acts as a ligand-gated ion channel. Belongs to the P2X receptor family.	0.795
GRIN1	P2RX4	ENSCAFP00000037473	ENSCAFP00000012316	Glutamate receptor ionotropic, NMDA 1; Component of NMDA receptor complexes that function as heterotetrameric, ligand-gated ion channels with high calcium permeability and voltage-dependent sensitivity to magnesium. Channel activation requires binding of the neurotransmitter glutamate to the epsilon subunit, glycine binding to the zeta subunit, plus membrane depolarization to eliminate channel inhibition by Mg(2+). Sensitivity to glutamate and channel kinetics depend on the subunit composition. Belongs to the glutamate-gated ion channel (TC 1.A.10.1) family. NR1/GRIN1 subfamily.	P2X purinoceptor; Receptor for ATP that acts as a ligand-gated ion channel.	0.794
GRIN1	P2RX5	ENSCAFP00000037473	ENSCAFP00000039858	Glutamate receptor ionotropic, NMDA 1; Component of NMDA receptor complexes that function as heterotetrameric, ligand-gated ion channels with high calcium permeability and voltage-dependent sensitivity to magnesium. Channel activation requires binding of the neurotransmitter glutamate to the epsilon subunit, glycine binding to the zeta subunit, plus membrane depolarization to eliminate channel inhibition by Mg(2+). Sensitivity to glutamate and channel kinetics depend on the subunit composition. Belongs to the glutamate-gated ion channel (TC 1.A.10.1) family. NR1/GRIN1 subfamily.	P2X purinoceptor; Receptor for ATP that acts as a ligand-gated ion channel.	0.803
GRIN1	P2RX6	ENSCAFP00000037473	ENSCAFP00000042799	Glutamate receptor ionotropic, NMDA 1; Component of NMDA receptor complexes that function as heterotetrameric, ligand-gated ion channels with high calcium permeability and voltage-dependent sensitivity to magnesium. Channel activation requires binding of the neurotransmitter glutamate to the epsilon subunit, glycine binding to the zeta subunit, plus membrane depolarization to eliminate channel inhibition by Mg(2+). Sensitivity to glutamate and channel kinetics depend on the subunit composition. Belongs to the glutamate-gated ion channel (TC 1.A.10.1) family. NR1/GRIN1 subfamily.	P2X purinoceptor; Receptor for ATP that acts as a ligand-gated ion channel.	0.841
GRIN1	P2RX7	ENSCAFP00000037473	ENSCAFP00000012359	Glutamate receptor ionotropic, NMDA 1; Component of NMDA receptor complexes that function as heterotetrameric, ligand-gated ion channels with high calcium permeability and voltage-dependent sensitivity to magnesium. Channel activation requires binding of the neurotransmitter glutamate to the epsilon subunit, glycine binding to the zeta subunit, plus membrane depolarization to eliminate channel inhibition by Mg(2+). Sensitivity to glutamate and channel kinetics depend on the subunit composition. Belongs to the glutamate-gated ion channel (TC 1.A.10.1) family. NR1/GRIN1 subfamily.	P2X purinoceptor; Receptor for ATP that acts as a ligand-gated ion channel. Belongs to the P2X receptor family.	0.711
GRIN2A	GRIN1	ENSCAFP00000028005	ENSCAFP00000037473	Glutamate ionotropic receptor NMDA type subunit 2A.	Glutamate receptor ionotropic, NMDA 1; Component of NMDA receptor complexes that function as heterotetrameric, ligand-gated ion channels with high calcium permeability and voltage-dependent sensitivity to magnesium. Channel activation requires binding of the neurotransmitter glutamate to the epsilon subunit, glycine binding to the zeta subunit, plus membrane depolarization to eliminate channel inhibition by Mg(2+). Sensitivity to glutamate and channel kinetics depend on the subunit composition. Belongs to the glutamate-gated ion channel (TC 1.A.10.1) family. NR1/GRIN1 subfamily.	0.999
GRIN2A	GRIN2D	ENSCAFP00000028005	ENSCAFP00000061970	Glutamate ionotropic receptor NMDA type subunit 2A.	Glutamate ionotropic receptor NMDA type subunit 2D; Belongs to the glutamate-gated ion channel (TC 1.A.10.1) family.	0.993
GRIN2A	GRIN3A	ENSCAFP00000028005	ENSCAFP00000003807	Glutamate ionotropic receptor NMDA type subunit 2A.	Glutamate ionotropic receptor NMDA type subunit 3A.	0.969
GRIN2A	P2RX1	ENSCAFP00000028005	ENSCAFP00000028598	Glutamate ionotropic receptor NMDA type subunit 2A.	P2X purinoceptor; Receptor for ATP that acts as a ligand-gated ion channel.	0.803
GRIN2A	P2RX2	ENSCAFP00000028005	ENSCAFP00000009417	Glutamate ionotropic receptor NMDA type subunit 2A.	P2X purinoceptor; Receptor for ATP that acts as a ligand-gated ion channel.	0.799
GRIN2A	P2RX3	ENSCAFP00000028005	ENSCAFP00000066381	Glutamate ionotropic receptor NMDA type subunit 2A.	P2X purinoceptor; Receptor for ATP that acts as a ligand-gated ion channel. Belongs to the P2X receptor family.	0.821
GRIN2A	P2RX4	ENSCAFP00000028005	ENSCAFP00000012316	Glutamate ionotropic receptor NMDA type subunit 2A.	P2X purinoceptor; Receptor for ATP that acts as a ligand-gated ion channel.	0.798
GRIN2A	P2RX5	ENSCAFP00000028005	ENSCAFP00000039858	Glutamate ionotropic receptor NMDA type subunit 2A.	P2X purinoceptor; Receptor for ATP that acts as a ligand-gated ion channel.	0.799
GRIN2A	P2RX6	ENSCAFP00000028005	ENSCAFP00000042799	Glutamate ionotropic receptor NMDA type subunit 2A.	P2X purinoceptor; Receptor for ATP that acts as a ligand-gated ion channel.	0.805
GRIN2A	P2RX7	ENSCAFP00000028005	ENSCAFP00000012359	Glutamate ionotropic receptor NMDA type subunit 2A.	P2X purinoceptor; Receptor for ATP that acts as a ligand-gated ion channel. Belongs to the P2X receptor family.	0.791