Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
PCLOPiccolo presynaptic cytomatrix protein. (4823 aa)    
Predicted Functional Partners:
RIMS2
Regulating synaptic membrane exocytosis 2.
   
 0.842
RAB3A
RAB3A, member RAS oncogene family.
   
 
 0.836
J9P5X7_CANLF
Uncharacterized protein.
   
 0.704
RIMS1
Regulating synaptic membrane exocytosis 1.
   
 0.704
RAB3B
RAB3B, member RAS oncogene family.
   
 
 0.682
RAB3C
RAB3C, member RAS oncogene family.
   
 
 0.682
BSN
Bassoon presynaptic cytomatrix protein.
   
 
 0.667
ERC1
ELKS/RAB6-interacting/CAST family member 1.
   
 
 0.655
RIMS3
Regulating synaptic membrane exocytosis 3.
   
 0.644
ERC2
ELKS/RAB6-interacting/CAST family member 2.
   
 
 0.619
Your Current Organism:
Canis lupus familiaris
NCBI taxonomy Id: 9615
Other names: C. lupus familiaris, Canis canis, Canis domesticus, Canis familiaris, beagle dog, beagle dogs, dog, dogs
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