STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
NR3C1Nuclear receptor subfamily 3 group C member 1. (781 aa)    
Predicted Functional Partners:
FKBP4
Peptidylprolyl isomerase.
    
 0.980
NCOR1
Nuclear receptor corepressor 1.
   
 0.972
FKBP5
Peptidylprolyl isomerase.
   
 
 0.961
NCOA2
Nuclear receptor coactivator 2.
   
 0.960
NCOA1
Nuclear receptor coactivator.
   
 0.956
NR3C2
Nuclear receptor subfamily 3 group C member 2.
  
 
0.953
NRIP1
Nuclear receptor interacting protein 1.
   
 
 0.935
MED1
Mediator of RNA polymerase II transcription subunit 1; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors.
   
 0.916
CREBBP
CREB binding protein.
   
 0.899
STAT3
Signal transducer and activator of transcription.
   
 
 0.878
Your Current Organism:
Canis lupus familiaris
NCBI taxonomy Id: 9615
Other names: C. lupus familiaris, Canis canis, Canis domesticus, Canis familiaris, beagle dog, beagle dogs, dog, dogs
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