STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
CUL4ACullin 4A; Belongs to the cullin family. (761 aa)    
Predicted Functional Partners:
DDB1
Damage specific DNA binding protein 1.
   
 0.999
DCAF1
DDB1 and CUL4 associated factor 1.
   
 0.997
CRBN
Cereblon.
   
 
 0.980
DDB2
Damage specific DNA binding protein 2.
    
 0.978
RBX1
Ring-box 1.
   
 0.962
CUL4B
Cullin 4B; Belongs to the cullin family.
  
 
0.954
ERCC8
ERCC excision repair 8, CSA ubiquitin ligase complex subunit.
    
 0.954
NEDD8
NEDD8 ubiquitin like modifier.
    
 0.923
DDA1
DET1 and DDB1 associated 1.
    
 0.883
CAND1
Cullin associated and neddylation dissociated 1.
   
 0.877
Your Current Organism:
Canis lupus familiaris
NCBI taxonomy Id: 9615
Other names: C. lupus familiaris, Canis canis, Canis domesticus, Canis familiaris, beagle dog, beagle dogs, dog, dogs
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.