STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
LAMP1Lysosomal associated membrane protein 1. (413 aa)    
Predicted Functional Partners:
LAMP2
Lysosomal associated membrane protein 2.
  
0.995
MTOR
Serine/threonine-protein kinase mTOR; Belongs to the PI3/PI4-kinase family.
    
 
 0.981
EEA1
Early endosome antigen 1.
      
 0.965
SEC13
SEC13 homolog, nuclear pore and COPII coat complex component; Belongs to the WD repeat SEC13 family.
    
 
 0.947
RPTOR
Regulatory associated protein of MTOR complex 1.
    
 
 0.944
NPRL2
NPR2 like, GATOR1 complex subunit.
    
 
 0.944
WDR24
WD repeat domain 24.
    
 
 0.933
DEPDC5
DEP domain containing 5.
    
 
 0.931
MIOS
Meiosis regulator for oocyte development.
    
 
 0.928
KPTN
Kaptin, actin binding protein.
    
 
 0.927
Your Current Organism:
Canis lupus familiaris
NCBI taxonomy Id: 9615
Other names: C. lupus familiaris, Canis canis, Canis domesticus, Canis familiaris, beagle dog, beagle dogs, dog, dogs
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.