STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
LAMP1Lysosomal associated membrane protein 1. (413 aa)    
Predicted Functional Partners:
EEA1
Early endosome antigen 1.
   
  
 0.998
CD63
Tetraspanin.
   
 
 0.976
MTOR
Serine/threonine-protein kinase mTOR; Belongs to the PI3/PI4-kinase family.
    
 
 0.971
LAMP2
Lysosomal associated membrane protein 2.
  
 
0.970
CTSD
Cathepsin D; Acid protease active in intracellular protein breakdown. Plays a role in APP processing following cleavage and activation by ADAM30 which leads to APP degradation; Belongs to the peptidase A1 family.
   
 
 0.968
NPRL2
NPR2 like, GATOR1 complex subunit.
    
 
 0.968
SEC13
SEC13 homolog, nuclear pore and COPII coat complex component; Belongs to the WD repeat SEC13 family.
   
 
 0.944
RPTOR
Regulatory associated protein of MTOR complex 1.
    
 
 0.940
DEPDC5
DEP domain containing 5.
    
 
 0.938
WDR24
WD repeat domain 24.
    
 
 0.936
Your Current Organism:
Canis lupus familiaris
NCBI taxonomy Id: 9615
Other names: C. lupus familiaris, Canis canis, Canis domesticus, Canis familiaris, beagle dog, beagle dogs, dog, dogs
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