NEUROD4 protein (Canis lupus familiaris) - STRING interaction network

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Score

NEUROD4

Neurogenic differentiation factor. (331 aa)

Predicted Functional Partners:

TCF3

0.757

NES

0.583

TCF4

0.572

TCF12

0.572

SLC12A5

0.553

PAX4

0.534

EP300

0.523

RFX6

0.510

GFAP

0.501

BDNF

0.470

Your Current Organism:

Canis lupus familiaris

NCBI taxonomy Id: 9615
Other names: C. lupus familiaris, Canis canis, Canis domesticus, Canis familiaris, beagle dog, beagle dogs, dog, dogs

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
BDNF	GFAP	ENSCAFP00000014984	ENSCAFP00000058935	Brain-derived neurotrophic factor; Important signaling molecule that activates signaling cascades downstream of NTRK2 (By similarity). During development, promotes the survival and differentiation of selected neuronal populations of the peripheral and central nervous systems. Participates in axonal growth, pathfinding and in the modulation of dendritic growth and morphology. Major regulator of synaptic transmission and plasticity at adult synapses in many regions of the CNS. The versatility of BDNF is emphasized by its contribution to a range of adaptive neuronal responses including lo [...]	Glial fibrillary acidic protein; Belongs to the intermediate filament family.	0.881
BDNF	NES	ENSCAFP00000014984	ENSCAFP00000024660	Brain-derived neurotrophic factor; Important signaling molecule that activates signaling cascades downstream of NTRK2 (By similarity). During development, promotes the survival and differentiation of selected neuronal populations of the peripheral and central nervous systems. Participates in axonal growth, pathfinding and in the modulation of dendritic growth and morphology. Major regulator of synaptic transmission and plasticity at adult synapses in many regions of the CNS. The versatility of BDNF is emphasized by its contribution to a range of adaptive neuronal responses including lo [...]	Nestin; Belongs to the intermediate filament family.	0.867
BDNF	NEUROD4	ENSCAFP00000014984	ENSCAFP00000009509	Brain-derived neurotrophic factor; Important signaling molecule that activates signaling cascades downstream of NTRK2 (By similarity). During development, promotes the survival and differentiation of selected neuronal populations of the peripheral and central nervous systems. Participates in axonal growth, pathfinding and in the modulation of dendritic growth and morphology. Major regulator of synaptic transmission and plasticity at adult synapses in many regions of the CNS. The versatility of BDNF is emphasized by its contribution to a range of adaptive neuronal responses including lo [...]	Neurogenic differentiation factor.	0.470
BDNF	PAX4	ENSCAFP00000014984	ENSCAFP00000002500	Brain-derived neurotrophic factor; Important signaling molecule that activates signaling cascades downstream of NTRK2 (By similarity). During development, promotes the survival and differentiation of selected neuronal populations of the peripheral and central nervous systems. Participates in axonal growth, pathfinding and in the modulation of dendritic growth and morphology. Major regulator of synaptic transmission and plasticity at adult synapses in many regions of the CNS. The versatility of BDNF is emphasized by its contribution to a range of adaptive neuronal responses including lo [...]	Paired box 4.	0.404
EP300	NEUROD4	ENSCAFP00000001585	ENSCAFP00000009509	E1A binding protein p300.	Neurogenic differentiation factor.	0.523
EP300	TCF12	ENSCAFP00000001585	ENSCAFP00000023912	E1A binding protein p300.	Transcription factor 12.	0.561
EP300	TCF3	ENSCAFP00000001585	ENSCAFP00000028831	E1A binding protein p300.	Transcription factor 3.	0.843
EP300	TCF4	ENSCAFP00000001585	ENSCAFP00000000209	E1A binding protein p300.	Transcription factor 4; Transcription factor that binds to the immunoglobulin enhancer Mu-E5/KE5-motif. Involved in the initiation of neuronal differentiation. Activates transcription by binding to the E box (5'- CANNTG-3') (By similarity). Binds to the thyroglobulin promoter.	0.561
GFAP	BDNF	ENSCAFP00000058935	ENSCAFP00000014984	Glial fibrillary acidic protein; Belongs to the intermediate filament family.	Brain-derived neurotrophic factor; Important signaling molecule that activates signaling cascades downstream of NTRK2 (By similarity). During development, promotes the survival and differentiation of selected neuronal populations of the peripheral and central nervous systems. Participates in axonal growth, pathfinding and in the modulation of dendritic growth and morphology. Major regulator of synaptic transmission and plasticity at adult synapses in many regions of the CNS. The versatility of BDNF is emphasized by its contribution to a range of adaptive neuronal responses including lo [...]	0.881
GFAP	NES	ENSCAFP00000058935	ENSCAFP00000024660	Glial fibrillary acidic protein; Belongs to the intermediate filament family.	Nestin; Belongs to the intermediate filament family.	0.938
GFAP	NEUROD4	ENSCAFP00000058935	ENSCAFP00000009509	Glial fibrillary acidic protein; Belongs to the intermediate filament family.	Neurogenic differentiation factor.	0.501
GFAP	PAX4	ENSCAFP00000058935	ENSCAFP00000002500	Glial fibrillary acidic protein; Belongs to the intermediate filament family.	Paired box 4.	0.587
NES	BDNF	ENSCAFP00000024660	ENSCAFP00000014984	Nestin; Belongs to the intermediate filament family.	Brain-derived neurotrophic factor; Important signaling molecule that activates signaling cascades downstream of NTRK2 (By similarity). During development, promotes the survival and differentiation of selected neuronal populations of the peripheral and central nervous systems. Participates in axonal growth, pathfinding and in the modulation of dendritic growth and morphology. Major regulator of synaptic transmission and plasticity at adult synapses in many regions of the CNS. The versatility of BDNF is emphasized by its contribution to a range of adaptive neuronal responses including lo [...]	0.867
NES	GFAP	ENSCAFP00000024660	ENSCAFP00000058935	Nestin; Belongs to the intermediate filament family.	Glial fibrillary acidic protein; Belongs to the intermediate filament family.	0.938
NES	NEUROD4	ENSCAFP00000024660	ENSCAFP00000009509	Nestin; Belongs to the intermediate filament family.	Neurogenic differentiation factor.	0.583
NES	PAX4	ENSCAFP00000024660	ENSCAFP00000002500	Nestin; Belongs to the intermediate filament family.	Paired box 4.	0.611
NES	TCF4	ENSCAFP00000024660	ENSCAFP00000000209	Nestin; Belongs to the intermediate filament family.	Transcription factor 4; Transcription factor that binds to the immunoglobulin enhancer Mu-E5/KE5-motif. Involved in the initiation of neuronal differentiation. Activates transcription by binding to the E box (5'- CANNTG-3') (By similarity). Binds to the thyroglobulin promoter.	0.562
NEUROD4	BDNF	ENSCAFP00000009509	ENSCAFP00000014984	Neurogenic differentiation factor.	Brain-derived neurotrophic factor; Important signaling molecule that activates signaling cascades downstream of NTRK2 (By similarity). During development, promotes the survival and differentiation of selected neuronal populations of the peripheral and central nervous systems. Participates in axonal growth, pathfinding and in the modulation of dendritic growth and morphology. Major regulator of synaptic transmission and plasticity at adult synapses in many regions of the CNS. The versatility of BDNF is emphasized by its contribution to a range of adaptive neuronal responses including lo [...]	0.470
NEUROD4	EP300	ENSCAFP00000009509	ENSCAFP00000001585	Neurogenic differentiation factor.	E1A binding protein p300.	0.523
NEUROD4	GFAP	ENSCAFP00000009509	ENSCAFP00000058935	Neurogenic differentiation factor.	Glial fibrillary acidic protein; Belongs to the intermediate filament family.	0.501