Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
PDS5BPDS5 cohesin associated factor B. (1461 aa)    
Predicted Functional Partners:
PDS5A
Uncharacterized protein.
  
0.997
SMC1A
Structural maintenance of chromosomes protein.
   
 0.992
STAG2
Stromal antigen 2.
   
 0.986
SMC3
Structural maintenance of chromosomes protein.
   
 
 0.985
WAPL
WAPL cohesin release factor.
   
 
 0.984
NIPBL
Nipped-B protein.
   
 0.982
STAG1
Stromal antigen 1.
   
 
 0.964
RAD21
RAD21 cohesin complex component.
   
 0.957
SMC1B
Structural maintenance of chromosomes protein.
   
 
 0.916
ESCO2
Establishment of sister chromatid cohesion N-acetyltransferase 2.
   
 0.861
Your Current Organism:
Canis lupus familiaris
NCBI taxonomy Id: 9615
Other names: C. lupus familiaris, Canis canis, Canis domesticus, Canis familiaris, beagle dog, beagle dogs, dog, dogs
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