STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
SEMA3CSemaphorin 3C; Belongs to the semaphorin family. (750 aa)    
Predicted Functional Partners:
NRP1
Neuropilin 1.
  
 
 0.967
NRP2
Neuropilin; Belongs to the neuropilin family.
    
 
 0.783
PLXND1
Plexin D1.
    
 0.737
PLXNA3
Plexin A3.
    
 0.626
SEMA3D
Semaphorin 3D; Belongs to the semaphorin family.
    
   0.578
SEMA3F
Semaphorin 3F; Belongs to the semaphorin family.
    
   0.578
CALCR
Calcitonin receptor; Belongs to the G-protein coupled receptor 2 family.
      
 0.577
FAM92B
Family with sequence similarity 92 member B.
      
 0.533
PRDM1
PR/SET domain 1.
      
 0.524
PLXNA2
Plexin A2.
    
 0.514
Your Current Organism:
Canis lupus familiaris
NCBI taxonomy Id: 9615
Other names: C. lupus familiaris, Canis canis, Canis domesticus, Canis familiaris, beagle dog, beagle dogs, dog, dogs
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.