| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| ATP12A | ATP1A1 | ENSCAFP00000011046 | ENSCAFP00000047882 | Sodium/potassium-transporting ATPase subunit alpha. | Sodium/potassium-transporting ATPase subunit alpha-1; This is the catalytic component of the active enzyme, which catalyzes the hydrolysis of ATP coupled with the exchange of sodium and potassium ions across the plasma membrane. This action creates the electrochemical gradient of sodium and potassium ions, providing the energy for active transport of various nutrients. | 0.573 |
| ATP12A | ATP1A3 | ENSCAFP00000011046 | ENSCAFP00000061865 | Sodium/potassium-transporting ATPase subunit alpha. | ATPase Na+/K+ transporting subunit alpha 3; Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. | 0.573 |
| ATP12A | ATP1A4 | ENSCAFP00000011046 | ENSCAFP00000046475 | Sodium/potassium-transporting ATPase subunit alpha. | Sodium/potassium-transporting ATPase subunit alpha. | 0.573 |
| ATP12A | ATP1B1 | ENSCAFP00000011046 | ENSCAFP00000022476 | Sodium/potassium-transporting ATPase subunit alpha. | Sodium/potassium-transporting ATPase subunit beta-1; This is the non-catalytic component of the active enzyme, which catalyzes the hydrolysis of ATP coupled with the exchange of Na(+) and K(+) ions across the plasma membrane. The beta subunit regulates, through assembly of alpha/beta heterodimers, the number of sodium pumps transported to the plasma membrane. | 0.924 |
| ATP12A | ATP1B2 | ENSCAFP00000011046 | ENSCAFP00000045466 | Sodium/potassium-transporting ATPase subunit alpha. | Sodium/potassium-transporting ATPase subunit beta; This is the non-catalytic component of the active enzyme, which catalyzes the hydrolysis of ATP coupled with the exchange of Na(+) and K(+) ions across the plasma membrane. Belongs to the X(+)/potassium ATPases subunit beta family. | 0.675 |
| ATP12A | ATP1B3 | ENSCAFP00000011046 | ENSCAFP00000011460 | Sodium/potassium-transporting ATPase subunit alpha. | Sodium/potassium-transporting ATPase subunit beta; This is the non-catalytic component of the active enzyme, which catalyzes the hydrolysis of ATP coupled with the exchange of Na(+) and K(+) ions across the plasma membrane. Belongs to the X(+)/potassium ATPases subunit beta family. | 0.675 |
| ATP12A | ATP4A | ENSCAFP00000011046 | ENSCAFP00000055733 | Sodium/potassium-transporting ATPase subunit alpha. | Potassium-transporting ATPase alpha chain 1; Catalyzes the hydrolysis of ATP coupled with the exchange of H(+) and K(+) ions across the plasma membrane. Responsible for acid production in the stomach; Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IIC subfamily. | 0.992 |
| ATP12A | ATP4B | ENSCAFP00000011046 | ENSCAFP00000009569 | Sodium/potassium-transporting ATPase subunit alpha. | Potassium-transporting ATPase subunit beta; Required for stabilization and maturation of the catalytic proton pump alpha subunit and may also involved in cell adhesion and establishing epithelial cell polarity; Belongs to the X(+)/potassium ATPases subunit beta family. | 0.998 |
| ATP12A | FXYD1 | ENSCAFP00000011046 | ENSCAFP00000060996 | Sodium/potassium-transporting ATPase subunit alpha. | Phospholemman; Associates with and regulates the activity of the sodium/potassium-transporting ATPase (NKA) which transports Na(+) out of the cell and K(+) into the cell. Inhibits NKA activity in its unphosphorylated state and stimulates activity when phosphorylated (By similarity). Reduces glutathionylation of the NKA beta-1 subunit ATP1B1, thus reversing glutathionylation-mediated inhibition of ATP1B1. Contributes to female sexual development by maintaining the excitability of neurons which secrete gonadotropin-releasing hormone (By similarity). | 0.649 |
| ATP12A | LHPP | ENSCAFP00000011046 | ENSCAFP00000052127 | Sodium/potassium-transporting ATPase subunit alpha. | Phospholysine phosphohistidine inorganic pyrophosphate phosphatase. | 0.903 |
| ATP1A1 | ATP12A | ENSCAFP00000047882 | ENSCAFP00000011046 | Sodium/potassium-transporting ATPase subunit alpha-1; This is the catalytic component of the active enzyme, which catalyzes the hydrolysis of ATP coupled with the exchange of sodium and potassium ions across the plasma membrane. This action creates the electrochemical gradient of sodium and potassium ions, providing the energy for active transport of various nutrients. | Sodium/potassium-transporting ATPase subunit alpha. | 0.573 |
| ATP1A1 | ATP1A3 | ENSCAFP00000047882 | ENSCAFP00000061865 | Sodium/potassium-transporting ATPase subunit alpha-1; This is the catalytic component of the active enzyme, which catalyzes the hydrolysis of ATP coupled with the exchange of sodium and potassium ions across the plasma membrane. This action creates the electrochemical gradient of sodium and potassium ions, providing the energy for active transport of various nutrients. | ATPase Na+/K+ transporting subunit alpha 3; Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. | 0.769 |
| ATP1A1 | ATP1A4 | ENSCAFP00000047882 | ENSCAFP00000046475 | Sodium/potassium-transporting ATPase subunit alpha-1; This is the catalytic component of the active enzyme, which catalyzes the hydrolysis of ATP coupled with the exchange of sodium and potassium ions across the plasma membrane. This action creates the electrochemical gradient of sodium and potassium ions, providing the energy for active transport of various nutrients. | Sodium/potassium-transporting ATPase subunit alpha. | 0.975 |
| ATP1A1 | ATP1B1 | ENSCAFP00000047882 | ENSCAFP00000022476 | Sodium/potassium-transporting ATPase subunit alpha-1; This is the catalytic component of the active enzyme, which catalyzes the hydrolysis of ATP coupled with the exchange of sodium and potassium ions across the plasma membrane. This action creates the electrochemical gradient of sodium and potassium ions, providing the energy for active transport of various nutrients. | Sodium/potassium-transporting ATPase subunit beta-1; This is the non-catalytic component of the active enzyme, which catalyzes the hydrolysis of ATP coupled with the exchange of Na(+) and K(+) ions across the plasma membrane. The beta subunit regulates, through assembly of alpha/beta heterodimers, the number of sodium pumps transported to the plasma membrane. | 0.999 |
| ATP1A1 | ATP1B2 | ENSCAFP00000047882 | ENSCAFP00000045466 | Sodium/potassium-transporting ATPase subunit alpha-1; This is the catalytic component of the active enzyme, which catalyzes the hydrolysis of ATP coupled with the exchange of sodium and potassium ions across the plasma membrane. This action creates the electrochemical gradient of sodium and potassium ions, providing the energy for active transport of various nutrients. | Sodium/potassium-transporting ATPase subunit beta; This is the non-catalytic component of the active enzyme, which catalyzes the hydrolysis of ATP coupled with the exchange of Na(+) and K(+) ions across the plasma membrane. Belongs to the X(+)/potassium ATPases subunit beta family. | 0.996 |
| ATP1A1 | ATP1B3 | ENSCAFP00000047882 | ENSCAFP00000011460 | Sodium/potassium-transporting ATPase subunit alpha-1; This is the catalytic component of the active enzyme, which catalyzes the hydrolysis of ATP coupled with the exchange of sodium and potassium ions across the plasma membrane. This action creates the electrochemical gradient of sodium and potassium ions, providing the energy for active transport of various nutrients. | Sodium/potassium-transporting ATPase subunit beta; This is the non-catalytic component of the active enzyme, which catalyzes the hydrolysis of ATP coupled with the exchange of Na(+) and K(+) ions across the plasma membrane. Belongs to the X(+)/potassium ATPases subunit beta family. | 0.997 |
| ATP1A1 | ATP4A | ENSCAFP00000047882 | ENSCAFP00000055733 | Sodium/potassium-transporting ATPase subunit alpha-1; This is the catalytic component of the active enzyme, which catalyzes the hydrolysis of ATP coupled with the exchange of sodium and potassium ions across the plasma membrane. This action creates the electrochemical gradient of sodium and potassium ions, providing the energy for active transport of various nutrients. | Potassium-transporting ATPase alpha chain 1; Catalyzes the hydrolysis of ATP coupled with the exchange of H(+) and K(+) ions across the plasma membrane. Responsible for acid production in the stomach; Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IIC subfamily. | 0.604 |
| ATP1A1 | ATP4B | ENSCAFP00000047882 | ENSCAFP00000009569 | Sodium/potassium-transporting ATPase subunit alpha-1; This is the catalytic component of the active enzyme, which catalyzes the hydrolysis of ATP coupled with the exchange of sodium and potassium ions across the plasma membrane. This action creates the electrochemical gradient of sodium and potassium ions, providing the energy for active transport of various nutrients. | Potassium-transporting ATPase subunit beta; Required for stabilization and maturation of the catalytic proton pump alpha subunit and may also involved in cell adhesion and establishing epithelial cell polarity; Belongs to the X(+)/potassium ATPases subunit beta family. | 0.980 |
| ATP1A1 | FXYD1 | ENSCAFP00000047882 | ENSCAFP00000060996 | Sodium/potassium-transporting ATPase subunit alpha-1; This is the catalytic component of the active enzyme, which catalyzes the hydrolysis of ATP coupled with the exchange of sodium and potassium ions across the plasma membrane. This action creates the electrochemical gradient of sodium and potassium ions, providing the energy for active transport of various nutrients. | Phospholemman; Associates with and regulates the activity of the sodium/potassium-transporting ATPase (NKA) which transports Na(+) out of the cell and K(+) into the cell. Inhibits NKA activity in its unphosphorylated state and stimulates activity when phosphorylated (By similarity). Reduces glutathionylation of the NKA beta-1 subunit ATP1B1, thus reversing glutathionylation-mediated inhibition of ATP1B1. Contributes to female sexual development by maintaining the excitability of neurons which secrete gonadotropin-releasing hormone (By similarity). | 0.994 |
| ATP1A1 | LHPP | ENSCAFP00000047882 | ENSCAFP00000052127 | Sodium/potassium-transporting ATPase subunit alpha-1; This is the catalytic component of the active enzyme, which catalyzes the hydrolysis of ATP coupled with the exchange of sodium and potassium ions across the plasma membrane. This action creates the electrochemical gradient of sodium and potassium ions, providing the energy for active transport of various nutrients. | Phospholysine phosphohistidine inorganic pyrophosphate phosphatase. | 0.549 |
