STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
FAM160A2Family with sequence similarity 160 member A2. (985 aa)    
Predicted Functional Partners:
AKTIP
AKT interacting protein.
    
 
 0.851
HOOK3
Hook microtubule tethering protein 3.
    
 
 0.832
HOOK2
Hook microtubule tethering protein 2.
    
 
 0.600
TNFSF13B
Tumor necrosis factor ligand 7A; Belongs to the tumor necrosis factor family.
    
   0.529
KCNS2
Potassium voltage-gated channel modifier subfamily S member 2; Belongs to the potassium channel family.
      
 0.515
RUSC2
RUN and SH3 domain containing 2.
      
 0.515
HOOK1
Hook microtubule tethering protein 1.
    
 
 0.483
BICDL2
BICD family like cargo adaptor 2.
      
 0.483
AP4M1
AP-4 complex subunit mu-1; Component of the adaptor protein complex 4 (AP-4). Adaptor protein complexes are vesicle coat components involved both in vesicle formation and cargo selection. They control the vesicular transport of proteins in different trafficking pathways. AP-4 forms a non clathrin- associated coat on vesicles departing the trans-Golgi network (TGN) and may be involved in the targeting of proteins from the trans-Golgi network (TGN) to the endosomal-lysosomal system (By similarity). It is also involved in protein sorting to the basolateral membrane in epithelial cells and [...]
    
 
 0.467
ZCCHC14
Zinc finger CCHC-type containing 14.
      
 0.457
Your Current Organism:
Canis lupus familiaris
NCBI taxonomy Id: 9615
Other names: C. lupus familiaris, Canis canis, Canis domesticus, Canis familiaris, beagle dog, beagle dogs, dog, dogs
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