CNGA4 protein (Canis lupus familiaris) - STRING interaction network

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Score

CNGA4

Cyclic nucleotide gated channel subunit alpha 4. (575 aa)

Predicted Functional Partners:

CNGA2

0.998

CNGB3

0.992

CNGB1

0.988

CALML5

0.913

CALML6

0.913

CNGA3

0.913

CNGA1

0.909

CALML4

0.864

RTP2

0.831

PDE2A

0.784

Your Current Organism:

Canis lupus familiaris

NCBI taxonomy Id: 9615
Other names: C. lupus familiaris, Canis canis, Canis domesticus, Canis familiaris, beagle dog, beagle dogs, dog, dogs

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
CALML4	CALML5	ENSCAFP00000025749	ENSCAFP00000007824	Calmodulin like 4.	Calmodulin like 5.	0.870
CALML4	CALML6	ENSCAFP00000025749	ENSCAFP00000028340	Calmodulin like 4.	Calmodulin like 6.	0.866
CALML4	CNGA1	ENSCAFP00000025749	ENSCAFP00000035274	Calmodulin like 4.	cGMP-gated cation channel alpha-1; Subunit of the rod cyclic GMP-gated cation channel, which is involved in the final stage of the phototransduction pathway. When light hits rod photoreceptors, cGMP concentrations decrease causing rapid closure of CNGA1/CNGB1 channels and, therefore, hyperpolarization of the membrane potential.	0.902
CALML4	CNGA2	ENSCAFP00000025749	ENSCAFP00000028255	Calmodulin like 4.	Cyclic nucleotide gated channel subunit alpha 2.	0.902
CALML4	CNGA3	ENSCAFP00000025749	ENSCAFP00000066106	Calmodulin like 4.	Cyclic nucleotide-gated channel alpha 3.	0.636
CALML4	CNGA4	ENSCAFP00000025749	ENSCAFP00000009581	Calmodulin like 4.	Cyclic nucleotide gated channel subunit alpha 4.	0.864
CALML4	CNGB1	ENSCAFP00000025749	ENSCAFP00000012647	Calmodulin like 4.	Cyclic nucleotide gated channel subunit beta 1.	0.912
CALML4	CNGB3	ENSCAFP00000025749	ENSCAFP00000013075	Calmodulin like 4.	Cyclic nucleotide-gated cation channel beta-3; Visual signal transduction is mediated by a G-protein coupled cascade using cGMP as second messenger. This protein can be activated by cGMP which leads to an opening of the cation channel and thereby causing a depolarization of rod photoreceptors. Induced a flickering channel gating, weakened the outward rectification in the presence of extracellular calcium, increased sensitivity for L-cis diltiazem and enhanced the cAMP efficacy of the channel when coexpressed with CNGA3. Essential for the generation of light-evoked electrical responses [...]	0.753
CALML5	CALML4	ENSCAFP00000007824	ENSCAFP00000025749	Calmodulin like 5.	Calmodulin like 4.	0.870
CALML5	CALML6	ENSCAFP00000007824	ENSCAFP00000028340	Calmodulin like 5.	Calmodulin like 6.	0.735
CALML5	CNGA1	ENSCAFP00000007824	ENSCAFP00000035274	Calmodulin like 5.	cGMP-gated cation channel alpha-1; Subunit of the rod cyclic GMP-gated cation channel, which is involved in the final stage of the phototransduction pathway. When light hits rod photoreceptors, cGMP concentrations decrease causing rapid closure of CNGA1/CNGB1 channels and, therefore, hyperpolarization of the membrane potential.	0.925
CALML5	CNGA2	ENSCAFP00000007824	ENSCAFP00000028255	Calmodulin like 5.	Cyclic nucleotide gated channel subunit alpha 2.	0.931
CALML5	CNGA3	ENSCAFP00000007824	ENSCAFP00000066106	Calmodulin like 5.	Cyclic nucleotide-gated channel alpha 3.	0.411
CALML5	CNGA4	ENSCAFP00000007824	ENSCAFP00000009581	Calmodulin like 5.	Cyclic nucleotide gated channel subunit alpha 4.	0.913
CALML5	CNGB1	ENSCAFP00000007824	ENSCAFP00000012647	Calmodulin like 5.	Cyclic nucleotide gated channel subunit beta 1.	0.939
CALML5	CNGB3	ENSCAFP00000007824	ENSCAFP00000013075	Calmodulin like 5.	Cyclic nucleotide-gated cation channel beta-3; Visual signal transduction is mediated by a G-protein coupled cascade using cGMP as second messenger. This protein can be activated by cGMP which leads to an opening of the cation channel and thereby causing a depolarization of rod photoreceptors. Induced a flickering channel gating, weakened the outward rectification in the presence of extracellular calcium, increased sensitivity for L-cis diltiazem and enhanced the cAMP efficacy of the channel when coexpressed with CNGA3. Essential for the generation of light-evoked electrical responses [...]	0.507
CALML6	CALML4	ENSCAFP00000028340	ENSCAFP00000025749	Calmodulin like 6.	Calmodulin like 4.	0.866
CALML6	CALML5	ENSCAFP00000028340	ENSCAFP00000007824	Calmodulin like 6.	Calmodulin like 5.	0.735
CALML6	CNGA1	ENSCAFP00000028340	ENSCAFP00000035274	Calmodulin like 6.	cGMP-gated cation channel alpha-1; Subunit of the rod cyclic GMP-gated cation channel, which is involved in the final stage of the phototransduction pathway. When light hits rod photoreceptors, cGMP concentrations decrease causing rapid closure of CNGA1/CNGB1 channels and, therefore, hyperpolarization of the membrane potential.	0.897
CALML6	CNGA2	ENSCAFP00000028340	ENSCAFP00000028255	Calmodulin like 6.	Cyclic nucleotide gated channel subunit alpha 2.	0.900