STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
SH3RF2SH3 domain containing ring finger 2. (733 aa)    
Predicted Functional Partners:
RHPN1
Rhophilin Rho GTPase binding protein 1.
   
 
 0.894
ARMCX4
Armadillo repeat containing X-linked 4.
    
 
 0.890
TRAPPC12
Trafficking protein particle complex 12.
      
 0.862
NRP2
Neuropilin; Belongs to the neuropilin family.
      
 0.778
TENM4
Teneurin transmembrane protein 4.
   
 
 0.778
NPNT
Nephronectin.
      
 0.771
ANKRD9
Ankyrin repeat domain 9.
    
 0.661
KCMF1
Potassium channel modulatory factor 1.
      
 0.613
UHRF2
Ubiquitin like with PHD and ring finger domains 2.
      
 0.581
COMMD5
COMM domain containing 5.
      
 0.519
Your Current Organism:
Canis lupus familiaris
NCBI taxonomy Id: 9615
Other names: C. lupus familiaris, Canis canis, Canis domesticus, Canis familiaris, beagle dog, beagle dogs, dog, dogs
Server load: low (20%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.