STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
PPP4R2Protein phosphatase 4 regulatory subunit 2. (416 aa)    
Predicted Functional Partners:
PPP4R3A
Protein phosphatase 4 regulatory subunit 3A.
   
 0.998
PPP4C
Serine/threonine-protein phosphatase.
   
 0.997
PPP4R3B
Protein phosphatase 4 regulatory subunit 3B.
   
 0.989
PPP4R3C
Protein phosphatase 4 regulatory subunit 3C.
   
 0.989
PTPA
Serine/threonine-protein phosphatase 2A activator; PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides.
   
 
 0.957
TBX19
T-box transcription factor TBX19; Transcriptional regulator involved in developmental processes. Can activate POMC gene expression and repress the alpha glycoprotein subunit and thyroid-stimulating hormone beta promoters (By similarity).
    
 
 0.883
DHX38
DEAH-box helicase 38.
   
 
 0.837
PPME1
Protein phosphatase methylesterase 1; Demethylates proteins that have been reversibly carboxymethylated.
    
 
 0.825
CCDC6
Coiled-coil domain containing 6.
    
 
 0.815
SLC4A1AP
Solute carrier family 4 member 1 adaptor protein.
   
   0.800
Your Current Organism:
Canis lupus familiaris
NCBI taxonomy Id: 9615
Other names: C. lupus familiaris, Canis canis, Canis domesticus, Canis familiaris, beagle dog, beagle dogs, dog, dogs
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.