HPX protein (Canis lupus familiaris) - STRING interaction network

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Predicted Interactions

gene neighborhood

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Score

HPX

Amyloid beta precursor protein binding family B member 1. (664 aa)

Predicted Functional Partners:

APP

0.997

KAT5

0.878

MAPK8

0.843

ACAP1

0.785

APLP1

0.712

APLP2

0.708

APBB2

0.604

MRE11

0.580

PTPRN

0.570

ADGRE3

0.563

Your Current Organism:

Canis lupus familiaris

NCBI taxonomy Id: 9615
Other names: C. lupus familiaris, Canis canis, Canis domesticus, Canis familiaris, beagle dog, beagle dogs, dog, dogs

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ACAP1	HPX	ENSCAFP00000023942	ENSCAFP00000009615	ArfGAP with coiled-coil, ankyrin repeat and PH domains 1.	Amyloid beta precursor protein binding family B member 1.	0.785
ADGRE3	HPX	ENSCAFP00000047203	ENSCAFP00000009615	Adhesion G protein-coupled receptor E3; Belongs to the G-protein coupled receptor 2 family.	Amyloid beta precursor protein binding family B member 1.	0.563
APBB2	APLP1	ENSCAFP00000031402	ENSCAFP00000066098	Amyloid beta precursor protein binding family B member 2.	Amyloid beta precursor like protein 1.	0.617
APBB2	APLP2	ENSCAFP00000031402	ENSCAFP00000014894	Amyloid beta precursor protein binding family B member 2.	Amyloid beta precursor like protein 2.	0.567
APBB2	APP	ENSCAFP00000031402	ENSCAFP00000012583	Amyloid beta precursor protein binding family B member 2.	Gamma-secretase C-terminal fragment 57; Functions as a cell surface receptor and performs physiological functions on the surface of neurons relevant to neurite growth, neuronal adhesion and axonogenesis. Interaction between APP molecules on neighboring cells promotes synaptogenesis. Involved in cell mobility and transcription regulation through protein-protein interactions (By similarity). Can promote transcription activation through binding to APBB1-KAT5 and inhibit Notch signaling through interaction with Numb (By similarity). Couples to apoptosis-inducing pathways such as those medi [...]	0.935
APBB2	HPX	ENSCAFP00000031402	ENSCAFP00000009615	Amyloid beta precursor protein binding family B member 2.	Amyloid beta precursor protein binding family B member 1.	0.604
APLP1	APBB2	ENSCAFP00000066098	ENSCAFP00000031402	Amyloid beta precursor like protein 1.	Amyloid beta precursor protein binding family B member 2.	0.617
APLP1	APLP2	ENSCAFP00000066098	ENSCAFP00000014894	Amyloid beta precursor like protein 1.	Amyloid beta precursor like protein 2.	0.411
APLP1	APP	ENSCAFP00000066098	ENSCAFP00000012583	Amyloid beta precursor like protein 1.	Gamma-secretase C-terminal fragment 57; Functions as a cell surface receptor and performs physiological functions on the surface of neurons relevant to neurite growth, neuronal adhesion and axonogenesis. Interaction between APP molecules on neighboring cells promotes synaptogenesis. Involved in cell mobility and transcription regulation through protein-protein interactions (By similarity). Can promote transcription activation through binding to APBB1-KAT5 and inhibit Notch signaling through interaction with Numb (By similarity). Couples to apoptosis-inducing pathways such as those medi [...]	0.418
APLP1	HPX	ENSCAFP00000066098	ENSCAFP00000009615	Amyloid beta precursor like protein 1.	Amyloid beta precursor protein binding family B member 1.	0.712
APLP2	APBB2	ENSCAFP00000014894	ENSCAFP00000031402	Amyloid beta precursor like protein 2.	Amyloid beta precursor protein binding family B member 2.	0.567
APLP2	APLP1	ENSCAFP00000014894	ENSCAFP00000066098	Amyloid beta precursor like protein 2.	Amyloid beta precursor like protein 1.	0.411
APLP2	APP	ENSCAFP00000014894	ENSCAFP00000012583	Amyloid beta precursor like protein 2.	Gamma-secretase C-terminal fragment 57; Functions as a cell surface receptor and performs physiological functions on the surface of neurons relevant to neurite growth, neuronal adhesion and axonogenesis. Interaction between APP molecules on neighboring cells promotes synaptogenesis. Involved in cell mobility and transcription regulation through protein-protein interactions (By similarity). Can promote transcription activation through binding to APBB1-KAT5 and inhibit Notch signaling through interaction with Numb (By similarity). Couples to apoptosis-inducing pathways such as those medi [...]	0.572
APLP2	HPX	ENSCAFP00000014894	ENSCAFP00000009615	Amyloid beta precursor like protein 2.	Amyloid beta precursor protein binding family B member 1.	0.708
APP	APBB2	ENSCAFP00000012583	ENSCAFP00000031402	Gamma-secretase C-terminal fragment 57; Functions as a cell surface receptor and performs physiological functions on the surface of neurons relevant to neurite growth, neuronal adhesion and axonogenesis. Interaction between APP molecules on neighboring cells promotes synaptogenesis. Involved in cell mobility and transcription regulation through protein-protein interactions (By similarity). Can promote transcription activation through binding to APBB1-KAT5 and inhibit Notch signaling through interaction with Numb (By similarity). Couples to apoptosis-inducing pathways such as those medi [...]	Amyloid beta precursor protein binding family B member 2.	0.935
APP	APLP1	ENSCAFP00000012583	ENSCAFP00000066098	Gamma-secretase C-terminal fragment 57; Functions as a cell surface receptor and performs physiological functions on the surface of neurons relevant to neurite growth, neuronal adhesion and axonogenesis. Interaction between APP molecules on neighboring cells promotes synaptogenesis. Involved in cell mobility and transcription regulation through protein-protein interactions (By similarity). Can promote transcription activation through binding to APBB1-KAT5 and inhibit Notch signaling through interaction with Numb (By similarity). Couples to apoptosis-inducing pathways such as those medi [...]	Amyloid beta precursor like protein 1.	0.418
APP	APLP2	ENSCAFP00000012583	ENSCAFP00000014894	Gamma-secretase C-terminal fragment 57; Functions as a cell surface receptor and performs physiological functions on the surface of neurons relevant to neurite growth, neuronal adhesion and axonogenesis. Interaction between APP molecules on neighboring cells promotes synaptogenesis. Involved in cell mobility and transcription regulation through protein-protein interactions (By similarity). Can promote transcription activation through binding to APBB1-KAT5 and inhibit Notch signaling through interaction with Numb (By similarity). Couples to apoptosis-inducing pathways such as those medi [...]	Amyloid beta precursor like protein 2.	0.572
APP	HPX	ENSCAFP00000012583	ENSCAFP00000009615	Gamma-secretase C-terminal fragment 57; Functions as a cell surface receptor and performs physiological functions on the surface of neurons relevant to neurite growth, neuronal adhesion and axonogenesis. Interaction between APP molecules on neighboring cells promotes synaptogenesis. Involved in cell mobility and transcription regulation through protein-protein interactions (By similarity). Can promote transcription activation through binding to APBB1-KAT5 and inhibit Notch signaling through interaction with Numb (By similarity). Couples to apoptosis-inducing pathways such as those medi [...]	Amyloid beta precursor protein binding family B member 1.	0.997
APP	KAT5	ENSCAFP00000012583	ENSCAFP00000064911	Gamma-secretase C-terminal fragment 57; Functions as a cell surface receptor and performs physiological functions on the surface of neurons relevant to neurite growth, neuronal adhesion and axonogenesis. Interaction between APP molecules on neighboring cells promotes synaptogenesis. Involved in cell mobility and transcription regulation through protein-protein interactions (By similarity). Can promote transcription activation through binding to APBB1-KAT5 and inhibit Notch signaling through interaction with Numb (By similarity). Couples to apoptosis-inducing pathways such as those medi [...]	Histone acetyltransferase; Belongs to the MYST (SAS/MOZ) family.	0.735
HPX	ACAP1	ENSCAFP00000009615	ENSCAFP00000023942	Amyloid beta precursor protein binding family B member 1.	ArfGAP with coiled-coil, ankyrin repeat and PH domains 1.	0.785