STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
SHQ1SHQ1, H/ACA ribonucleoprotein assembly factor. (579 aa)    
Predicted Functional Partners:
DKC1
Dyskerin pseudouridine synthase 1.
   
 0.997
GAR1
H/ACA ribonucleoprotein complex subunit; Required for ribosome biogenesis. Part of a complex which catalyzes pseudouridylation of rRNA. This involves the isomerization of uridine such that the ribose is subsequently attached to C5, instead of the normal N1. Pseudouridine ("psi") residues may serve to stabilize the conformation of rRNAs.
   
 
 0.939
NOP10
NOP10 ribonucleoprotein.
   
 
 0.894
TRUB1
TruB pseudouridine synthase family member 1.
   
 
 0.876
GXYLT2
Glucoside xylosyltransferase 2.
      
 0.812
PDZRN3
PDZ domain containing ring finger 3.
      
 0.805
TRUB2
TruB pseudouridine synthase family member 2.
   
 
 0.799
UBE2R2
Ubiquitin conjugating enzyme E2 R2; Belongs to the ubiquitin-conjugating enzyme family.
      
 0.781
OSBP2
Oxysterol-binding protein; Belongs to the OSBP family.
      
 0.761
NHP2
Ribonucloprotein; Common component of the spliceosome and rRNA processing machinery; Belongs to the eukaryotic ribosomal protein eL8 family.
   
 
 0.741
Your Current Organism:
Canis lupus familiaris
NCBI taxonomy Id: 9615
Other names: C. lupus familiaris, Canis canis, Canis domesticus, Canis familiaris, beagle dog, beagle dogs, dog, dogs
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.