STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
LTA4HLeukotriene A(4) hydrolase; Belongs to the peptidase M1 family. (701 aa)    
Predicted Functional Partners:
ALOX5
Arachidonate 5-lipoxygenase.
     
 0.969
LTC4S
Leukotriene C4 synthase.
     
 0.968
PTGR1
Prostaglandin reductase 1.
   
 
 0.934
PTGR2
Uncharacterized protein.
   
 
 0.918
ZADH2
Zinc binding alcohol dehydrogenase domain containing 2.
     
 0.881
ALOX12
Arachidonate 15-lipoxygenase.
     
 0.841
TRIT1
tRNA isopentenyltransferase 1; Belongs to the IPP transferase family.
 
 
  
 0.841
CYP4F22
Cytochrome P450 family 4 subfamily F member 22; Belongs to the cytochrome P450 family.
    
 0.822
ALOX5AP
Arachidonate 5-lipoxygenase activating protein.
      
 0.815
ALOXE3
Arachidonate lipoxygenase 3.
     
 0.704
Your Current Organism:
Canis lupus familiaris
NCBI taxonomy Id: 9615
Other names: C. lupus familiaris, Canis canis, Canis domesticus, Canis familiaris, beagle dog, beagle dogs, dog, dogs
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