STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
THUMPD2THUMP domain containing 2. (502 aa)    
Predicted Functional Partners:
RGS1
Regulator of G protein signaling 1.
      
 0.707
KLF6
Kruppel like factor 6.
      
 0.679
TXNIP
Thioredoxin interacting protein.
      
 0.678
GADD45B
Growth arrest and DNA damage inducible beta.
      
 0.674
NUS1
NUS1 dehydrodolichyl diphosphate synthase subunit.
   
    0.612
DHDDS
Alkyl transferase; Belongs to the UPP synthase family.
   
    0.610
RPUSD1
RNA pseudouridine synthase domain containing 1.
  
 
 0.577
QTRT1
Queuine tRNA-ribosyltransferase catalytic subunit 1; Catalytic subunit of the queuine tRNA-ribosyltransferase (TGT) that catalyzes the base-exchange of a guanine (G) residue with queuine (Q) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2- cyclopenten-1-yl)amino)methyl)-7-deazaguanosine). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, formi [...]
  
  
 0.557
PNPT1
Polyribonucleotide nucleotidyltransferase 1.
  
    0.539
APMAP
Adipocyte plasma membrane associated protein.
  
    0.536
Your Current Organism:
Canis lupus familiaris
NCBI taxonomy Id: 9615
Other names: C. lupus familiaris, Canis canis, Canis domesticus, Canis familiaris, beagle dog, beagle dogs, dog, dogs
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.