STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
FRMD4BFERM domain containing 4B. (1035 aa)    
Predicted Functional Partners:
CYTH4
Cytohesin 4.
    
 
 0.556
PLEKHA5
Pleckstrin homology domain containing A5.
    
 0.555
FRMD6
FERM domain containing 6.
    
 0.550
TMTC4
Transmembrane O-mannosyltransferase targeting cadherins 4.
      
 0.546
CDC25A
Cell division cycle 25A.
      
 0.525
POU2F2
POU domain protein.
      
 0.513
CYTH2
Cytohesin 2.
    
 
 0.509
CYTH3
Cytohesin 3.
    
 
 0.509
CYTH1
Cytohesin 1.
    
 
 0.509
MAP3K8
Mitogen-activated protein kinase kinase kinase 8.
    
 
 0.474
Your Current Organism:
Canis lupus familiaris
NCBI taxonomy Id: 9615
Other names: C. lupus familiaris, Canis canis, Canis domesticus, Canis familiaris, beagle dog, beagle dogs, dog, dogs
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