STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
MTA3Metastasis associated 1 family member 3. (771 aa)    
Predicted Functional Partners:
MTA2
Metastasis associated 1 family member 2.
  
0.999
MTA1
Metastasis associated 1.
   
 0.997
CHD4
Chromodomain helicase DNA binding protein 4.
   
 0.994
CHD3
Chromodomain helicase DNA binding protein 3.
   
 0.987
HDAC1
Histone deacetylase 1; Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. Histone deacetylases act via the formation of large multiprotein complexes.
   
 0.974
HDAC2
Histone deacetylase 2.
   
 0.974
CHD5
Chromodomain helicase DNA binding protein 5.
   
 0.957
GATAD2B
GATA zinc finger domain containing 2B.
   
 
 0.950
GATAD2A
GATA zinc finger domain containing 2A.
   
 
 0.950
CDK2AP1-2
Cyclin-dependent kinase 2-associated protein; Belongs to the CDK2AP family.
    
 0.875
Your Current Organism:
Canis lupus familiaris
NCBI taxonomy Id: 9615
Other names: C. lupus familiaris, Canis canis, Canis domesticus, Canis familiaris, beagle dog, beagle dogs, dog, dogs
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.