Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
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[Homology]
Score
NEURL3Neuralized E3 ubiquitin protein ligase 3. (308 aa)    
Predicted Functional Partners:
HERC6
HECT and RLD domain containing E3 ubiquitin protein ligase family member 6.
    
 
 0.609
PARP12
Poly(ADP-ribose) polymerase family member 12.
      
 0.535
PIWIL2
Piwi like RNA-mediated gene silencing 2; Belongs to the argonaute family.
      
 0.476
QSOX1
Sulfhydryl oxidase.
      
 0.475
BCL2L14
BCL2 like 14.
      
 0.461
TRIM22
Tripartite motif containing 22.
      
 0.445
DCP2
Decapping mRNA 2.
      
 0.424
ADAR
Adenosine deaminase RNA specific.
      
 0.423
RNF208
Ring finger protein 208.
      
 0.410
RCHY1
Ring finger and CHY zinc finger domain containing 1.
      
 0.408
Your Current Organism:
Canis lupus familiaris
NCBI taxonomy Id: 9615
Other names: C. lupus familiaris, Canis canis, Canis domesticus, Canis familiaris, beagle dog, beagle dogs, dog, dogs
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