STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
DCHS1Dachsous cadherin-related 1. (3294 aa)    
Predicted Functional Partners:
TCTN2
Tectonic family member 2.
    
 
 0.802
RTTN
Rotatin.
      
 0.777
DCHS2
Dachsous cadherin-related 2.
     
  0.751
LMCD1
LIM and cysteine rich domains 1.
   
 
 0.709
FAT4
FAT atypical cadherin 4.
   
 
0.704
TNS1
Tensin 1.
   
 
 0.613
SH3PXD2B
SH3 and PX domains 2B.
   
  
 0.607
B3GAT3
Galactosylgalactosylxylosylprotein 3-beta-glucuronosyltransferase; Belongs to the glycosyltransferase 43 family.
      
 0.592
SLC52A1
Uncharacterized protein.
      
 0.591
PTPN12
Tyrosine-protein phosphatase non-receptor type 12; Dephosphorylates a range of proteins, and thereby regulates cellular signaling cascades.
    
 
 0.557
Your Current Organism:
Canis lupus familiaris
NCBI taxonomy Id: 9615
Other names: C. lupus familiaris, Canis canis, Canis domesticus, Canis familiaris, beagle dog, beagle dogs, dog, dogs
Server load: medium (42%) [HD]