STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
DCHS1Dachsous cadherin-related 1. (3294 aa)    
Predicted Functional Partners:
DCHS2
Dachsous cadherin-related 2.
  
  
 
0.902
TCTN2
Tectonic family member 2.
    
 
 0.789
RTTN
Rotatin.
      
 0.736
LMCD1
LIM and cysteine rich domains 1.
   
 
 0.713
PTPN12
Tyrosine-protein phosphatase non-receptor type 12; Dephosphorylates a range of proteins, and thereby regulates cellular signaling cascades.
    
 
 0.594
SH3PXD2B
SH3 and PX domains 2B.
   
  
 0.593
TNS1
Tensin 1.
   
 
 0.591
PCDH15
Protocadherin related 15.
   
 
0.578
MOB2
MOB kinase activator 2.
   
  
 0.569
SLC52A1
Uncharacterized protein.
      
 0.567
Your Current Organism:
Canis lupus familiaris
NCBI taxonomy Id: 9615
Other names: C. lupus familiaris, Canis canis, Canis domesticus, Canis familiaris, beagle dog, beagle dogs, dog, dogs
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.