| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| RAB5A | RAB5B | ENSCAFP00000008690 | ENSCAFP00000000123 | Ras-related protein Rab-5A; Small GTPase which cycles between active GTP-bound and inactive GDP-bound states. In its active state, binds to a variety of effector proteins to regulate cellular responses such as of intracellular membrane trafficking, from the formation of transport vesicles to their fusion with membranes. Active GTP-bound form is able to recruit to membranes different sets of downstream effectors directly responsible for vesicle formation, movement, tethering and fusion. RAB5A is required for the fusion of plasma membranes and early endosomes. Contributes to the regulati [...] | RAB5B, member RAS oncogene family. | 0.881 |
| RAB5A | TGFBRAP1 | ENSCAFP00000008690 | ENSCAFP00000003101 | Ras-related protein Rab-5A; Small GTPase which cycles between active GTP-bound and inactive GDP-bound states. In its active state, binds to a variety of effector proteins to regulate cellular responses such as of intracellular membrane trafficking, from the formation of transport vesicles to their fusion with membranes. Active GTP-bound form is able to recruit to membranes different sets of downstream effectors directly responsible for vesicle formation, movement, tethering and fusion. RAB5A is required for the fusion of plasma membranes and early endosomes. Contributes to the regulati [...] | Transforming growth factor beta receptor associated protein 1. | 0.935 |
| RAB5A | VPS11 | ENSCAFP00000008690 | ENSCAFP00000018221 | Ras-related protein Rab-5A; Small GTPase which cycles between active GTP-bound and inactive GDP-bound states. In its active state, binds to a variety of effector proteins to regulate cellular responses such as of intracellular membrane trafficking, from the formation of transport vesicles to their fusion with membranes. Active GTP-bound form is able to recruit to membranes different sets of downstream effectors directly responsible for vesicle formation, movement, tethering and fusion. RAB5A is required for the fusion of plasma membranes and early endosomes. Contributes to the regulati [...] | Vacuolar protein sorting-associated protein 11 homolog; Plays a role in vesicle-mediated protein trafficking to lysosomal compartments including the endocytic membrane transport and autophagic pathways. Believed to act as a core component of the putative HOPS and CORVET endosomal tethering complexes. Belongs to the VPS11 family. | 0.943 |
| RAB5A | VPS16 | ENSCAFP00000008690 | ENSCAFP00000009824 | Ras-related protein Rab-5A; Small GTPase which cycles between active GTP-bound and inactive GDP-bound states. In its active state, binds to a variety of effector proteins to regulate cellular responses such as of intracellular membrane trafficking, from the formation of transport vesicles to their fusion with membranes. Active GTP-bound form is able to recruit to membranes different sets of downstream effectors directly responsible for vesicle formation, movement, tethering and fusion. RAB5A is required for the fusion of plasma membranes and early endosomes. Contributes to the regulati [...] | Vacuolar protein sorting-associated protein 16 homolog; Plays a role in vesicle-mediated protein trafficking to lysosomal compartments including the endocytic membrane transport and autophagic pathways. Believed to act as a core component of the putative HOPS and CORVET endosomal tethering complexes. Belongs to the VPS16 family. | 0.946 |
| RAB5A | VPS18 | ENSCAFP00000008690 | ENSCAFP00000054950 | Ras-related protein Rab-5A; Small GTPase which cycles between active GTP-bound and inactive GDP-bound states. In its active state, binds to a variety of effector proteins to regulate cellular responses such as of intracellular membrane trafficking, from the formation of transport vesicles to their fusion with membranes. Active GTP-bound form is able to recruit to membranes different sets of downstream effectors directly responsible for vesicle formation, movement, tethering and fusion. RAB5A is required for the fusion of plasma membranes and early endosomes. Contributes to the regulati [...] | VPS18 core subunit of CORVET and HOPS complexes. | 0.951 |
| RAB5A | VPS33A | ENSCAFP00000008690 | ENSCAFP00000011731 | Ras-related protein Rab-5A; Small GTPase which cycles between active GTP-bound and inactive GDP-bound states. In its active state, binds to a variety of effector proteins to regulate cellular responses such as of intracellular membrane trafficking, from the formation of transport vesicles to their fusion with membranes. Active GTP-bound form is able to recruit to membranes different sets of downstream effectors directly responsible for vesicle formation, movement, tethering and fusion. RAB5A is required for the fusion of plasma membranes and early endosomes. Contributes to the regulati [...] | Uncharacterized protein; Belongs to the STXBP/unc-18/SEC1 family. | 0.929 |
| RAB5A | VPS33B | ENSCAFP00000008690 | ENSCAFP00000062971 | Ras-related protein Rab-5A; Small GTPase which cycles between active GTP-bound and inactive GDP-bound states. In its active state, binds to a variety of effector proteins to regulate cellular responses such as of intracellular membrane trafficking, from the formation of transport vesicles to their fusion with membranes. Active GTP-bound form is able to recruit to membranes different sets of downstream effectors directly responsible for vesicle formation, movement, tethering and fusion. RAB5A is required for the fusion of plasma membranes and early endosomes. Contributes to the regulati [...] | VPS33B late endosome and lysosome associated; Belongs to the STXBP/unc-18/SEC1 family. | 0.698 |
| RAB5A | VPS39 | ENSCAFP00000008690 | ENSCAFP00000033030 | Ras-related protein Rab-5A; Small GTPase which cycles between active GTP-bound and inactive GDP-bound states. In its active state, binds to a variety of effector proteins to regulate cellular responses such as of intracellular membrane trafficking, from the formation of transport vesicles to their fusion with membranes. Active GTP-bound form is able to recruit to membranes different sets of downstream effectors directly responsible for vesicle formation, movement, tethering and fusion. RAB5A is required for the fusion of plasma membranes and early endosomes. Contributes to the regulati [...] | VPS39 subunit of HOPS complex. | 0.637 |
| RAB5A | VPS41 | ENSCAFP00000008690 | ENSCAFP00000005335 | Ras-related protein Rab-5A; Small GTPase which cycles between active GTP-bound and inactive GDP-bound states. In its active state, binds to a variety of effector proteins to regulate cellular responses such as of intracellular membrane trafficking, from the formation of transport vesicles to their fusion with membranes. Active GTP-bound form is able to recruit to membranes different sets of downstream effectors directly responsible for vesicle formation, movement, tethering and fusion. RAB5A is required for the fusion of plasma membranes and early endosomes. Contributes to the regulati [...] | Vacuolar protein sorting-associated protein 41 homolog; Plays a role in vesicle-mediated protein trafficking to lysosomal compartments including the endocytic membrane transport pathways; Belongs to the VPS41 family. | 0.471 |
| RAB5A | VPS8 | ENSCAFP00000008690 | ENSCAFP00000039848 | Ras-related protein Rab-5A; Small GTPase which cycles between active GTP-bound and inactive GDP-bound states. In its active state, binds to a variety of effector proteins to regulate cellular responses such as of intracellular membrane trafficking, from the formation of transport vesicles to their fusion with membranes. Active GTP-bound form is able to recruit to membranes different sets of downstream effectors directly responsible for vesicle formation, movement, tethering and fusion. RAB5A is required for the fusion of plasma membranes and early endosomes. Contributes to the regulati [...] | VPS8 subunit of CORVET complex. | 0.923 |
| RAB5B | RAB5A | ENSCAFP00000000123 | ENSCAFP00000008690 | RAB5B, member RAS oncogene family. | Ras-related protein Rab-5A; Small GTPase which cycles between active GTP-bound and inactive GDP-bound states. In its active state, binds to a variety of effector proteins to regulate cellular responses such as of intracellular membrane trafficking, from the formation of transport vesicles to their fusion with membranes. Active GTP-bound form is able to recruit to membranes different sets of downstream effectors directly responsible for vesicle formation, movement, tethering and fusion. RAB5A is required for the fusion of plasma membranes and early endosomes. Contributes to the regulati [...] | 0.881 |
| RAB5B | TGFBRAP1 | ENSCAFP00000000123 | ENSCAFP00000003101 | RAB5B, member RAS oncogene family. | Transforming growth factor beta receptor associated protein 1. | 0.935 |
| RAB5B | VPS11 | ENSCAFP00000000123 | ENSCAFP00000018221 | RAB5B, member RAS oncogene family. | Vacuolar protein sorting-associated protein 11 homolog; Plays a role in vesicle-mediated protein trafficking to lysosomal compartments including the endocytic membrane transport and autophagic pathways. Believed to act as a core component of the putative HOPS and CORVET endosomal tethering complexes. Belongs to the VPS11 family. | 0.943 |
| RAB5B | VPS16 | ENSCAFP00000000123 | ENSCAFP00000009824 | RAB5B, member RAS oncogene family. | Vacuolar protein sorting-associated protein 16 homolog; Plays a role in vesicle-mediated protein trafficking to lysosomal compartments including the endocytic membrane transport and autophagic pathways. Believed to act as a core component of the putative HOPS and CORVET endosomal tethering complexes. Belongs to the VPS16 family. | 0.946 |
| RAB5B | VPS18 | ENSCAFP00000000123 | ENSCAFP00000054950 | RAB5B, member RAS oncogene family. | VPS18 core subunit of CORVET and HOPS complexes. | 0.951 |
| RAB5B | VPS33A | ENSCAFP00000000123 | ENSCAFP00000011731 | RAB5B, member RAS oncogene family. | Uncharacterized protein; Belongs to the STXBP/unc-18/SEC1 family. | 0.941 |
| RAB5B | VPS33B | ENSCAFP00000000123 | ENSCAFP00000062971 | RAB5B, member RAS oncogene family. | VPS33B late endosome and lysosome associated; Belongs to the STXBP/unc-18/SEC1 family. | 0.698 |
| RAB5B | VPS39 | ENSCAFP00000000123 | ENSCAFP00000033030 | RAB5B, member RAS oncogene family. | VPS39 subunit of HOPS complex. | 0.637 |
| RAB5B | VPS41 | ENSCAFP00000000123 | ENSCAFP00000005335 | RAB5B, member RAS oncogene family. | Vacuolar protein sorting-associated protein 41 homolog; Plays a role in vesicle-mediated protein trafficking to lysosomal compartments including the endocytic membrane transport pathways; Belongs to the VPS41 family. | 0.471 |
| RAB5B | VPS8 | ENSCAFP00000000123 | ENSCAFP00000039848 | RAB5B, member RAS oncogene family. | VPS8 subunit of CORVET complex. | 0.923 |
