STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
MEDAGMesenteric estrogen dependent adipogenesis. (303 aa)    
Predicted Functional Partners:
ZC2HC1C
Zinc finger C2HC-type containing 1C.
      
 0.773
UHRF1BP1L
UHRF1 binding protein 1 like.
      
 0.692
PAMR1
Peptidase domain containing associated with muscle regeneration 1; Belongs to the peptidase S1 family.
   
  
 0.619
SUCO
SUN domain containing ossification factor.
      
 0.607
PDGFRL
Platelet derived growth factor receptor like.
   
  
 0.604
ZBTB21
Zinc finger and BTB domain containing 21.
      
 0.602
GNG12
Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction.
      
 0.578
ARPC5L
Actin-related protein 2/3 complex subunit 5; Functions as component of the Arp2/3 complex which is involved in regulation of actin polymerization and together with an activating nucleation-promoting factor (NPF) mediates the formation of branched actin networks. Arp2/3 complex plays a critical role in the control of cell morphogenesis via the modulation of cell polarity development.
      
 0.572
SORCS2
Sortilin related VPS10 domain containing receptor 2.
      
 0.532
CDX2
Caudal type homeobox 2.
      
 0.528
Your Current Organism:
Canis lupus familiaris
NCBI taxonomy Id: 9615
Other names: C. lupus familiaris, Canis canis, Canis domesticus, Canis familiaris, beagle dog, beagle dogs, dog, dogs
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.