STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
STK32ASerine/threonine kinase 32A; Belongs to the protein kinase superfamily. (394 aa)    
Predicted Functional Partners:
ARHGAP25
Rho-GAP domain-containing protein.
      
 0.832
DPYSL3
Dihydropyrimidinase like 3.
      
 0.827
STAC2
SH3 and cysteine rich domain 2.
    
 
 0.793
PRKAR1A
Protein kinase cAMP-dependent type I regulatory subunit alpha.
 
  
 
 0.765
LOC484191
Uncharacterized protein.
 
  
  0.759
A3GALT2
Alpha 1,3-galactosyltransferase 2.
    
 
 0.728
CREG2
Cellular repressor of E1A stimulated genes 2; Belongs to the CREG family.
   
  
 0.686
VCAM1
Vascular cell adhesion protein 1; Important in cell-cell recognition. Appears to function in leukocyte-endothelial cell adhesion. Interacts with integrin alpha- 4/beta-1 (ITGA4/ITGB1) on leukocytes, and mediates both adhesion and signal transduction. The VCAM1/ITGA4/ITGB1 interaction may play a pathophysiologic role both in immune responses and in leukocyte emigration to sites of inflammation (By similarity).
      
 0.671
HHLA1
HERV-H LTR-associating 1.
    
 0.633
RPTOR
Regulatory associated protein of MTOR complex 1.
    
 0.613
Your Current Organism:
Canis lupus familiaris
NCBI taxonomy Id: 9615
Other names: C. lupus familiaris, Canis canis, Canis domesticus, Canis familiaris, beagle dog, beagle dogs, dog, dogs
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.