Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
CBX5Chromobox 5. (191 aa)    
Predicted Functional Partners:
DSN1
DSN1 component of MIS12 kinetochore complex.
    
 
 0.963
CHAF1B
Chromatin assembly factor 1 subunit B.
    
 
 0.946
PRR14
Proline rich 14.
    
 
 0.945
CHAF1A
Chromatin assembly factor 1 subunit A.
   
 
 0.936
CBX1
Chromobox 1.
   
 
 0.929
NSL1
NSL1 component of MIS12 kinetochore complex.
    
 
 0.909
POGZ
Pogo transposable element derived with ZNF domain.
    
 
 0.908
EHMT2
Euchromatic histone lysine methyltransferase 2.
    
 
 0.881
SGO1
Shugoshin 1.
    
 
 0.879
MECP2
Methyl-CpG-binding protein 2; Chromosomal protein that binds to methylated DNA. It can bind specifically to a single methyl-CpG pair. It is not influenced by sequences flanking the methyl-CpGs. Binds both 5-methylcytosine (5mC) and 5-hydroxymethylcytosine (5hmC)-containing DNA, with a preference for 5-methylcytosine (5mC).
   
 
 0.865
Your Current Organism:
Canis lupus familiaris
NCBI taxonomy Id: 9615
Other names: C. lupus familiaris, Canis canis, Canis domesticus, Canis familiaris, beagle dog, beagle dogs, dog, dogs
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