STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
EFCAB1EF-hand calcium binding domain 1. (271 aa)    
Predicted Functional Partners:
TTC25
Tetratricopeptide repeat domain 25.
   
 0.956
C9orf116
Chromosome 9 open reading frame 116.
    
 
 0.950
EFHC2
EF-hand domain containing 2.
   
 
 0.943
CCDC114
Coiled-coil domain containing 114.
    
 
 0.937
C16H4orf47
Chromosome 16 C4orf47 homolog.
    
 
 0.935
EFHB
EF-hand domain family member B.
   
 
 0.933
IQUB
IQ motif and ubiquitin domain containing.
   
 
 0.931
EFCAB10
EF-hand calcium binding domain 10.
   
 
 0.921
EFCAB3
EF-hand calcium binding domain 3.
    
 0.920
C34H5orf49
Chromosome 34 C5orf49 homolog.
    
 
 0.899
Your Current Organism:
Canis lupus familiaris
NCBI taxonomy Id: 9615
Other names: C. lupus familiaris, Canis canis, Canis domesticus, Canis familiaris, beagle dog, beagle dogs, dog, dogs
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.