STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
HOXC12Homeobox C12. (277 aa)    
Predicted Functional Partners:
RNPEPL1
Arginyl aminopeptidase like 1.
   
  
 0.699
EZH2
Enhancer of zeste 2 polycomb repressive complex 2 subunit.
    
 
 0.669
CLYBL
Citrate lyase beta like.
    
 
 0.592
ATP6V1H
ATPase H+ transporting V1 subunit H.
      
 0.591
CAPN10
Calpain 10; Belongs to the peptidase C2 family.
      
 0.532
SLIRP
SRA stem-loop interacting RNA binding protein.
      
 0.525
TAF10
Transcription initiation factor TFIID subunit 10; TFIID is a multimeric protein complex that plays a central role in mediating promoter responses to various activators and repressors; Belongs to the TAF10 family.
      
 0.517
TBX4
T-box transcription factor TBX4; Involved in the transcriptional regulation of genes required for mesoderm differentiation. Probably plays a role in limb pattern formation (By similarity).
    
 
 0.476
HAND2
Heart and neural crest derivatives expressed 2.
    
 
 0.475
RGS20
Regulator of G protein signaling 20.
      
 0.466
Your Current Organism:
Canis lupus familiaris
NCBI taxonomy Id: 9615
Other names: C. lupus familiaris, Canis canis, Canis domesticus, Canis familiaris, beagle dog, beagle dogs, dog, dogs
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.