STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
SPINK5Serine peptidase inhibitor, Kazal type 5. (1063 aa)    
Predicted Functional Partners:
KLK8
Uncharacterized protein; Belongs to the peptidase S1 family.
   
 
 0.707
CDSN
Corneodesmosin.
   
  
 0.670
KLK14
Kallikrein related-peptidase 14; Belongs to the peptidase S1 family.
   
 
 0.597
KLK10
Kallikrein related peptidase 10; Belongs to the peptidase S1 family.
   
 
 0.593
KRTDAP
Keratinocyte differentiation-associated protein; May act as a soluble regulator of keratinocyte differentiation. May play an important role in embryonic skin morphogenesis (By similarity).
   
  
 0.591
ST14
Suppression of tumorigenicity 14.
    
 
 0.584
LOC100687463
C-type lectin domain-containing protein.
  
   
 0.572
KLK5
Kallikrein related peptidase 5; Belongs to the peptidase S1 family.
   
 
 0.563
REG3A
Regenerating islet-derived 3 alpha.
  
   
 0.553
CRNN
Cornulin.
  
  
 0.548
Your Current Organism:
Canis lupus familiaris
NCBI taxonomy Id: 9615
Other names: C. lupus familiaris, Canis canis, Canis domesticus, Canis familiaris, beagle dog, beagle dogs, dog, dogs
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.