STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
SPINK5Serine peptidase inhibitor, Kazal type 5. (1063 aa)    
Predicted Functional Partners:
KLK5
Kallikrein related peptidase 5; Belongs to the peptidase S1 family.
   
 0.951
CDSN
Corneodesmosin.
   
  
 0.725
KLK14
Kallikrein related-peptidase 14; Belongs to the peptidase S1 family.
   
 
 0.698
KLK8
Uncharacterized protein; Belongs to the peptidase S1 family.
   
 
 0.624
LOC100687463
C-type lectin domain-containing protein.
  
   
 0.608
REG3A
Regenerating islet-derived 3 alpha.
  
   
 0.579
ACTL9
Actin like 9; Belongs to the actin family.
      
 0.570
SPINK4
Serine peptidase inhibitor, Kazal type 4.
      
 0.564
SPINK2
Serine peptidase inhibitor, Kazal type 2.
      
 0.562
KLK11
Kallikrein related peptidase 11; Belongs to the peptidase S1 family.
   
 
 0.562
Your Current Organism:
Canis lupus familiaris
NCBI taxonomy Id: 9615
Other names: C. lupus familiaris, Canis canis, Canis domesticus, Canis familiaris, beagle dog, beagle dogs, dog, dogs
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.