STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
LOC111092171Double-headed protease inhibitor, submandibular gland; This inhibitor is composed of two homologous actively inhibiting halves: one which inhibits trypsin, the other which inhibits elastase. (143 aa)    
Predicted Functional Partners:
LOC475521
Cationic trypsin.
    
 
 0.504
LOC479649
Peptidase S1 domain-containing protein; Belongs to the peptidase S1 family.
    
 
 0.492
CTRB2
Chymotrypsin 2 chain A; Belongs to the peptidase S1 family.
    
 
 0.490
CSN2
Beta-casein; Important role in determination of the surface properties of the casein micelles.
      
 0.483
ACR
Acrosin; Acrosin is the major protease of mammalian spermatozoa. It is a serine protease of trypsin-like cleavage specificity, it is synthesized in a zymogen form, proacrosin and stored in the acrosome.
    
 
 0.482
PRSS2
Anionic trypsin.
    
 
 0.466
TMPRSS15
Transmembrane serine protease 15; Belongs to the peptidase S1 family.
    
 
 0.449
TFF1
Trefoil factor 1; Stabilizer of the mucous gel overlying the gastrointestinal mucosa that provides a physical barrier against various noxious agents.
      
 0.446
SPINK13
Kazal-like domain-containing protein.
      
 0.424
AHCYL1
Adenosylhomocysteinase like 1; Belongs to the adenosylhomocysteinase family.
      
 0.414
Your Current Organism:
Canis lupus familiaris
NCBI taxonomy Id: 9615
Other names: C. lupus familiaris, Canis canis, Canis domesticus, Canis familiaris, beagle dog, beagle dogs, dog, dogs
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