STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
TMC2Transmembrane channel-like protein. (907 aa)    
Predicted Functional Partners:
LHFPL5
LHFPL tetraspan subfamily member 5.
   
  
 0.786
PCDH15
Protocadherin related 15.
    
 
 0.718
CDH23
Cadherin related 23.
    
 
 0.677
CIB2
Calcium and integrin binding family member 2.
    
 
 0.671
ESPN
Espin.
   
 0.651
SLC6A5
Transporter; Belongs to the sodium:neurotransmitter symporter (SNF) (TC 2.A.22) family.
   
  
 0.611
NTSR1
Neurotensin receptor 1; Belongs to the G-protein coupled receptor 1 family.
    
 
 0.594
SULT1C3
Sulfotransferase; Belongs to the sulfotransferase 1 family.
   
  
 0.542
WFS1
Wolframin ER transmembrane glycoprotein.
    
 
 0.508
RTP3
Receptor transporter protein 3.
      
 0.487
Your Current Organism:
Canis lupus familiaris
NCBI taxonomy Id: 9615
Other names: C. lupus familiaris, Canis canis, Canis domesticus, Canis familiaris, beagle dog, beagle dogs, dog, dogs
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.