STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
NFKBIDNFKB inhibitor delta. (493 aa)    
Predicted Functional Partners:
REL
REL proto-oncogene, NF-kB subunit.
   
 0.894
NFKB2
Nuclear factor kappa B subunit 2.
   
 
 0.855
NFKB1
Nuclear factor NF-kappa-B p105 subunit; NF-kappa-B is a pleiotropic transcription factor present in almost all cell types and is the endpoint of a series of signal transduction events that are initiated by a vast array of stimuli related to many biological processes such as inflammation, immunity, differentiation, cell growth, tumorigenesis and apoptosis. NF-kappa-B is a homo- or heterodimeric complex formed by the Rel-like domain- containing proteins RELA/p65, RELB, NFKB1/p105, NFKB1/p50, REL and NFKB2/p52 and the heterodimeric p65-p50 complex appears to be most abundant one. The dime [...]
   
 
 0.837
SETD6
SET domain containing 6, protein lysine methyltransferase.
    
 
 0.812
PRODH2
Proline dehydrogenase; Converts proline to delta-1-pyrroline-5-carboxylate.
   
 
 0.770
SS18
SS18 subunit of BAF chromatin remodeling complex.
    
   0.734
RELB
RELB proto-oncogene, NF-kB subunit.
   
 0.710
RELA
RELA proto-oncogene, NF-kB subunit.
   
 0.709
HLCS
Holocarboxylase synthetase.
      
 0.692
NFKBIB
NFKB inhibitor beta.
  
  
 0.583
Your Current Organism:
Canis lupus familiaris
NCBI taxonomy Id: 9615
Other names: C. lupus familiaris, Canis canis, Canis domesticus, Canis familiaris, beagle dog, beagle dogs, dog, dogs
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