STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
CDX2Caudal type homeobox 2. (463 aa)    
Predicted Functional Partners:
EPC2
Enhancer of polycomb homolog.
      
 0.610
FGF4
Fibroblast growth factor; Belongs to the heparin-binding growth factors family.
    
 
 0.586
BMP4
TGF_BETA_2 domain-containing protein.
      
 0.566
FOXA2
Forkhead box A2.
   
  
 0.556
POU5F1
POU domain protein.
    
 
 0.537
SOX17
SRY-box 17.
    
 
 0.534
FGF5
Fibroblast growth factor 5; Plays an important role in the regulation of cell proliferation and cell differentiation. Required for normal regulation of the hair growth cycle. Functions as an inhibitor of hair elongation by promoting progression from anagen, the growth phase of the hair follicle, into catagen the apoptosis-induced regression phase. Belongs to the heparin-binding growth factors family.
    
 
 0.533
CDX1
Caudal type homeobox 1.
   
   0.530
MEDAG
Mesenteric estrogen dependent adipogenesis.
      
 0.528
B3GLCT
Beta 3-glucosyltransferase.
      
 0.528
Your Current Organism:
Canis lupus familiaris
NCBI taxonomy Id: 9615
Other names: C. lupus familiaris, Canis canis, Canis domesticus, Canis familiaris, beagle dog, beagle dogs, dog, dogs
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